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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LANCL1 All Species: 20.91
Human Site: Y21 Identified Species: 35.38
UniProt: O43813 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43813 NP_001130046.1 399 45283 Y21 N K S L A E G Y F D A A G R L
Chimpanzee Pan troglodytes XP_516065 399 45271 Y21 N K S L A E G Y F D A A G R L
Rhesus Macaque Macaca mulatta XP_001110118 399 45249 Y21 N K S L A E G Y F D A A G R L
Dog Lupus familis XP_536055 399 45422 Y21 N K S L A E S Y F D C A G R L
Cat Felis silvestris
Mouse Mus musculus O89112 399 45323 Y21 N K S L A E N Y F D S T G R L
Rat Rattus norvegicus Q9QX69 399 45221 Y21 N K S L A E N Y F D S T G R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508377 456 51270 E72 S A R T R Q L E G N R R S Q Q
Chicken Gallus gallus NP_001026416 343 38587
Frog Xenopus laevis NP_001082380 402 45423 A20 Y N H Q A S T A F N S T G Q L
Zebra Danio Brachydanio rerio Q90ZL2 405 45733 L23 G L G C A Q D L F D M Q G N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0Y7 419 47592 F21 A G G E N T P F A S D E E H I
Honey Bee Apis mellifera XP_624030 404 46400 V23 N A T V N F V V N T A T N E I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797679 400 44476 N31 F S A E L A T N I I Q N G K L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001149305 401 44438 L27 P Q G I R G L L S L P Y T R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.7 91.2 N.A. 91.4 91.4 N.A. 54.1 68.6 68.4 64.6 N.A. 36.2 40.8 N.A. 49
Protein Similarity: 100 99.7 100 95.7 N.A. 96.4 95.4 N.A. 66.6 78.1 81.8 78.5 N.A. 54.1 62.3 N.A. 66
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 0 0 26.6 33.3 N.A. 0 13.3 N.A. 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 26.6 0 46.6 40 N.A. 13.3 33.3 N.A. 26.6
Percent
Protein Identity: N.A. 39.4 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 55.1 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 8 0 58 8 0 8 8 0 29 29 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 50 8 0 0 0 0 % D
% Glu: 0 0 0 15 0 43 0 8 0 0 0 8 8 8 0 % E
% Phe: 8 0 0 0 0 8 0 8 58 0 0 0 0 0 0 % F
% Gly: 8 8 22 0 0 8 22 0 8 0 0 0 65 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 8 0 0 0 0 8 8 0 0 0 0 15 % I
% Lys: 0 43 0 0 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 8 0 43 8 0 15 15 0 8 0 0 0 0 72 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 50 8 0 0 15 0 15 8 8 15 0 8 8 8 0 % N
% Pro: 8 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % P
% Gln: 0 8 0 8 0 15 0 0 0 0 8 8 0 15 8 % Q
% Arg: 0 0 8 0 15 0 0 0 0 0 8 8 0 50 0 % R
% Ser: 8 8 43 0 0 8 8 0 8 8 22 0 8 0 0 % S
% Thr: 0 0 8 8 0 8 15 0 0 8 0 29 8 0 0 % T
% Val: 0 0 0 8 0 0 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 43 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _