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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LANCL1
All Species:
26.36
Human Site:
T135
Identified Species:
44.62
UniProt:
O43813
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43813
NP_001130046.1
399
45283
T135
K
Q
A
E
D
C
I
T
R
L
I
H
L
N
K
Chimpanzee
Pan troglodytes
XP_516065
399
45271
T135
K
Q
A
E
D
C
I
T
R
L
I
H
L
N
K
Rhesus Macaque
Macaca mulatta
XP_001110118
399
45249
T135
K
Q
A
E
D
C
I
T
R
L
I
H
L
N
K
Dog
Lupus familis
XP_536055
399
45422
T135
K
Q
A
E
D
C
I
T
R
L
I
H
L
N
K
Cat
Felis silvestris
Mouse
Mus musculus
O89112
399
45323
T135
K
Q
A
E
E
C
I
T
R
L
I
H
L
N
K
Rat
Rattus norvegicus
Q9QX69
399
45221
T135
K
Q
A
E
D
C
I
T
R
L
I
H
L
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508377
456
51270
L195
S
A
G
R
L
V
L
L
Q
L
N
K
L
D
P
Chicken
Gallus gallus
NP_001026416
343
38587
K93
H
V
A
H
E
Y
V
K
K
S
L
S
C
L
T
Frog
Xenopus laevis
NP_001082380
402
45423
K134
K
E
A
E
D
C
V
K
S
L
L
Q
L
H
P
Zebra Danio
Brachydanio rerio
Q90ZL2
405
45733
N137
Q
E
S
D
E
C
L
N
R
L
L
Q
L
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0Y7
419
47592
A139
E
E
L
S
D
D
L
A
N
F
K
S
G
I
P
Honey Bee
Apis mellifera
XP_624030
404
46400
S139
T
T
T
Q
D
I
I
S
R
I
K
S
L
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797679
400
44476
D146
T
E
A
Q
Q
C
I
D
K
L
Q
S
F
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149305
401
44438
S141
L
R
V
T
Q
Y
L
S
S
F
D
E
I
T
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.7
91.2
N.A.
91.4
91.4
N.A.
54.1
68.6
68.4
64.6
N.A.
36.2
40.8
N.A.
49
Protein Similarity:
100
99.7
100
95.7
N.A.
96.4
95.4
N.A.
66.6
78.1
81.8
78.5
N.A.
54.1
62.3
N.A.
66
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
13.3
6.6
46.6
26.6
N.A.
6.6
26.6
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
33.3
73.3
73.3
N.A.
26.6
53.3
N.A.
53.3
Percent
Protein Identity:
N.A.
39.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
55.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
65
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
65
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
8
58
8
0
8
0
0
8
0
0
8
0
% D
% Glu:
8
29
0
50
22
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
15
0
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
43
0
8
0
% H
% Ile:
0
0
0
0
0
8
58
0
0
8
43
0
8
8
8
% I
% Lys:
50
0
0
0
0
0
0
15
15
0
15
8
0
0
43
% K
% Leu:
8
0
8
0
8
0
29
8
0
72
22
0
72
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
8
0
0
43
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% P
% Gln:
8
43
0
15
15
0
0
0
8
0
8
15
0
8
0
% Q
% Arg:
0
8
0
8
0
0
0
0
58
0
0
0
0
0
8
% R
% Ser:
8
0
8
8
0
0
0
15
15
8
0
29
0
8
8
% S
% Thr:
15
8
8
8
0
0
0
43
0
0
0
0
0
8
8
% T
% Val:
0
8
8
0
0
8
15
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _