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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPOP
All Species:
19.39
Human Site:
Y353
Identified Species:
35.56
UniProt:
O43791
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43791
NP_001007227.1
374
42132
Y353
P
H
L
V
A
E
A
Y
R
S
L
A
S
A
Q
Chimpanzee
Pan troglodytes
XP_001168292
392
44160
T353
H
A
S
D
V
L
E
T
S
G
W
K
S
M
V
Rhesus Macaque
Macaca mulatta
XP_001094028
392
44244
T353
H
A
S
D
V
L
E
T
S
G
W
K
S
M
V
Dog
Lupus familis
XP_865058
415
46627
Y394
P
H
L
V
A
E
A
Y
R
S
L
A
S
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q2M2N2
392
44655
T353
Q
A
T
D
I
M
E
T
S
G
W
K
S
M
I
Rat
Rattus norvegicus
NP_001127919
392
44725
T353
Q
A
T
D
I
M
E
T
S
G
W
K
S
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509972
374
42178
F353
P
H
L
V
A
E
A
F
R
A
L
A
S
A
Q
Chicken
Gallus gallus
XP_423281
374
42132
Y353
P
H
L
V
A
E
A
Y
R
S
L
A
S
A
Q
Frog
Xenopus laevis
Q7ZX06
374
42136
Y353
P
H
L
V
A
E
A
Y
R
S
L
A
S
A
Q
Zebra Danio
Brachydanio rerio
Q7T330
374
42116
Y353
P
H
L
V
A
E
A
Y
R
S
L
A
S
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFP2
829
89649
F808
S
H
L
I
A
E
A
F
R
A
L
A
T
Q
Q
Honey Bee
Apis mellifera
XP_395294
396
44485
F375
P
H
L
I
A
E
A
F
R
A
L
A
T
Q
Q
Nematode Worm
Caenorhab. elegans
P34568
451
51044
F424
P
K
L
L
E
E
V
F
R
A
L
A
T
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.1
95.4
90.1
N.A.
79.5
79.5
N.A.
84.7
99.7
98.6
97.3
N.A.
36.6
76.5
54.7
N.A.
Protein Similarity:
100
95.4
95.4
90.1
N.A.
88.5
88.5
N.A.
93
100
99.4
98.9
N.A.
41.1
85.8
68.7
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
6.6
6.6
N.A.
86.6
100
100
100
N.A.
60
66.6
46.6
N.A.
P-Site Similarity:
100
6.6
6.6
100
N.A.
6.6
6.6
N.A.
100
100
100
100
N.A.
86.6
93.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
0
0
62
0
62
0
0
31
0
70
0
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
70
31
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% G
% His:
16
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
16
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
31
0
0
0
% K
% Leu:
0
0
70
8
0
16
0
0
0
0
70
0
0
0
0
% L
% Met:
0
0
0
0
0
16
0
0
0
0
0
0
0
31
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
0
0
0
0
0
24
70
% Q
% Arg:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% R
% Ser:
8
0
16
0
0
0
0
0
31
39
0
0
77
0
0
% S
% Thr:
0
0
16
0
0
0
0
31
0
0
0
0
24
0
0
% T
% Val:
0
0
0
47
16
0
8
0
0
0
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _