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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIAS All Species: 26.97
Human Site: S30 Identified Species: 49.44
UniProt: O43766 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43766 NP_006850.2 372 41911 S30 S P V R P L S S L P D K K K E
Chimpanzee Pan troglodytes XP_526552 372 41906 S30 S P V R P L S S L P D K K K E
Rhesus Macaque Macaca mulatta XP_001091994 372 41800 S30 S P V R P L S S L P D E K K E
Dog Lupus familis XP_536255 373 41947 S30 S P F R T V S S L P D K K K E
Cat Felis silvestris
Mouse Mus musculus Q99M04 373 41861 L30 T V R A L S S L P D K K K E F
Rat Rattus norvegicus Q5XIH4 373 41855 L30 S V R A L S S L P D E K K K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512706 391 44185 S41 Y R F R R L S S L P D E K K E
Chicken Gallus gallus XP_423226 385 43052 S43 N Q Y G T S S S L R E E T K K
Frog Xenopus laevis NP_001085534 372 41784 S30 T P Y R A L S S L P D E K K E
Zebra Danio Brachydanio rerio NP_001103871 397 44192 T50 S S S S S P S T H N D R K K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524183 377 42715 I30 N A E K L E E I R E R L A K G
Honey Bee Apis mellifera XP_625022 367 41898 N31 L H Y I K K K N F S Q K L K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32875 414 46229 T66 A T S Q L T G T S G K R R K G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.9 93.8 N.A. 90 90.8 N.A. 80.8 83.3 82.2 73.3 N.A. 62.3 63.1 N.A. N.A.
Protein Similarity: 100 99.7 99.1 96.2 N.A. 94.9 95.7 N.A. 87.4 88.8 89.7 83.1 N.A. 75.5 75.2 N.A. N.A.
P-Site Identity: 100 100 93.3 80 N.A. 20 33.3 N.A. 66.6 26.6 73.3 33.3 N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 33.3 40 N.A. 73.3 53.3 86.6 53.3 N.A. 20 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 49.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 62.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 16 8 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 16 54 0 0 0 16 % D
% Glu: 0 0 8 0 0 8 8 0 0 8 16 31 0 8 47 % E
% Phe: 0 0 16 0 0 0 0 0 8 0 0 0 0 0 16 % F
% Gly: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 16 % G
% His: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 8 8 8 0 0 0 16 47 70 93 8 % K
% Leu: 8 0 0 0 31 39 0 16 54 0 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 39 0 0 24 8 0 0 16 47 0 0 0 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 8 16 47 8 0 0 0 8 8 8 16 8 0 0 % R
% Ser: 47 8 16 8 8 24 77 54 8 8 0 0 0 0 0 % S
% Thr: 16 8 0 0 16 8 0 16 0 0 0 0 8 0 0 % T
% Val: 0 16 24 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 24 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _