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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX2
All Species:
13.03
Human Site:
Y54
Identified Species:
23.89
UniProt:
O43763
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43763
NP_057254.1
284
30251
Y54
N
G
A
F
S
G
G
Y
H
G
A
S
G
Y
G
Chimpanzee
Pan troglodytes
XP_001161223
284
30206
Y54
S
G
A
F
S
G
G
Y
H
G
A
S
G
Y
G
Rhesus Macaque
Macaca mulatta
XP_001110250
284
30204
Y54
S
G
A
F
S
G
G
Y
H
G
A
S
G
Y
G
Dog
Lupus familis
XP_855075
284
30159
F54
S
A
A
F
S
G
G
F
H
G
T
S
S
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61663
284
30342
F54
S
A
A
F
S
S
G
F
H
G
A
S
G
Y
A
Rat
Rattus norvegicus
O88181
384
41445
H87
T
D
G
P
Q
H
H
H
H
L
H
H
G
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
Y55
G
C
I
V
S
G
A
Y
N
T
M
T
G
G
Y
Chicken
Gallus gallus
O93367
297
32351
A66
L
G
G
P
R
G
G
A
P
Y
P
A
L
P
G
Frog
Xenopus laevis
Q8JJ64
306
34004
H92
W
Y
S
Y
T
L
A
H
G
G
H
T
P
R
T
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
R59
V
G
E
I
N
F
P
R
F
E
L
P
T
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
S228
G
G
K
S
T
T
G
S
N
G
F
T
S
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Sea Urchin
Strong. purpuratus
Q26656
405
44721
I112
N
G
Y
S
E
G
P
I
Y
G
S
T
R
H
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
91.1
N.A.
92.9
25.5
N.A.
46.7
57.5
27.1
22.5
N.A.
21.4
N.A.
26
25.6
Protein Similarity:
100
100
99.3
93.6
N.A.
95
33.8
N.A.
55.2
65.6
37.9
33
N.A.
28.2
N.A.
36.6
36.5
P-Site Identity:
100
93.3
93.3
66.6
N.A.
66.6
13.3
N.A.
26.6
26.6
6.6
6.6
N.A.
20
N.A.
0
26.6
P-Site Similarity:
100
100
100
80
N.A.
80
20
N.A.
40
33.3
40
13.3
N.A.
46.6
N.A.
0
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
39
0
0
0
16
8
0
0
31
8
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
39
0
8
0
16
8
0
8
0
0
8
0
% F
% Gly:
16
54
16
0
0
54
54
0
8
62
0
0
47
8
39
% G
% His:
0
0
0
0
0
8
8
16
47
0
16
8
0
8
0
% H
% Ile:
0
0
8
8
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
8
0
0
0
8
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
16
0
0
0
8
0
0
0
16
0
0
0
0
0
0
% N
% Pro:
0
0
0
16
0
0
16
0
8
0
8
8
8
8
8
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
16
8
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
8
8
8
% R
% Ser:
31
0
8
16
47
8
0
8
0
0
8
39
16
0
8
% S
% Thr:
8
0
0
0
16
8
0
0
0
8
8
31
8
0
8
% T
% Val:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
8
0
0
0
31
8
8
0
0
0
39
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _