KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX2
All Species:
43.03
Human Site:
Y181
Identified Species:
78.89
UniProt:
O43763
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43763
NP_057254.1
284
30251
Y181
R
R
F
L
R
Q
K
Y
L
A
S
A
E
R
A
Chimpanzee
Pan troglodytes
XP_001161223
284
30206
Y181
R
R
F
L
R
Q
K
Y
L
A
S
A
E
R
A
Rhesus Macaque
Macaca mulatta
XP_001110250
284
30204
Y181
R
R
F
L
R
Q
K
Y
L
A
S
A
E
R
A
Dog
Lupus familis
XP_855075
284
30159
Y181
R
R
F
L
R
Q
K
Y
L
A
S
A
E
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q61663
284
30342
Y181
R
R
F
L
R
Q
K
Y
L
A
S
A
E
R
A
Rat
Rattus norvegicus
O88181
384
41445
Y253
R
S
F
E
R
Q
K
Y
L
S
V
Q
D
R
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
Y234
K
R
F
H
R
Q
K
Y
L
A
S
A
E
R
A
Chicken
Gallus gallus
O93367
297
32351
Y196
K
R
F
H
R
Q
K
Y
L
A
S
A
E
R
A
Frog
Xenopus laevis
Q8JJ64
306
34004
Y202
S
T
F
D
M
K
R
Y
L
S
S
S
E
R
A
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
Y194
S
T
F
D
M
K
R
Y
L
S
S
S
E
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
Y492
S
T
F
D
L
K
R
Y
L
S
S
S
E
R
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
A73
Q
K
T
K
R
K
K
A
R
T
T
F
S
G
K
Sea Urchin
Strong. purpuratus
Q26656
405
44721
Y277
S
T
F
E
V
K
R
Y
L
S
S
S
E
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
91.1
N.A.
92.9
25.5
N.A.
46.7
57.5
27.1
22.5
N.A.
21.4
N.A.
26
25.6
Protein Similarity:
100
100
99.3
93.6
N.A.
95
33.8
N.A.
55.2
65.6
37.9
33
N.A.
28.2
N.A.
36.6
36.5
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
86.6
86.6
46.6
46.6
N.A.
46.6
N.A.
13.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
93.3
93.3
73.3
73.3
N.A.
73.3
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
54
0
54
0
0
85
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
16
0
0
0
0
0
0
0
0
85
0
0
% E
% Phe:
0
0
93
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
16
8
0
8
0
39
70
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
39
8
0
0
0
93
0
0
0
0
0
0
% L
% Met:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
62
0
0
0
0
0
8
0
0
0
% Q
% Arg:
47
54
0
0
70
0
31
0
8
0
0
0
0
93
0
% R
% Ser:
31
8
0
0
0
0
0
0
0
39
85
31
8
0
0
% S
% Thr:
0
31
8
0
0
0
0
0
0
8
8
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _