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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX2
All Species:
18.79
Human Site:
S65
Identified Species:
34.44
UniProt:
O43763
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43763
NP_057254.1
284
30251
S65
S
G
Y
G
P
A
G
S
L
A
P
L
P
G
S
Chimpanzee
Pan troglodytes
XP_001161223
284
30206
S65
S
G
Y
G
P
A
G
S
L
A
P
L
P
G
S
Rhesus Macaque
Macaca mulatta
XP_001110250
284
30204
S65
S
G
Y
G
P
A
G
S
L
A
P
L
P
G
S
Dog
Lupus familis
XP_855075
284
30159
S65
S
S
Y
G
P
A
G
S
L
A
P
L
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q61663
284
30342
S65
S
G
Y
A
P
A
G
S
L
A
S
L
P
R
G
Rat
Rattus norvegicus
O88181
384
41445
P98
H
G
Q
Q
P
P
P
P
S
A
P
P
A
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
A66
T
G
G
Y
S
A
S
A
C
F
R
W
R
E
Q
Chicken
Gallus gallus
O93367
297
32351
A77
A
L
P
G
P
F
P
A
I
A
A
P
F
E
E
Frog
Xenopus laevis
Q8JJ64
306
34004
D103
T
P
R
T
E
V
P
D
K
S
L
L
L
G
P
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
P70
P
T
Q
R
F
A
L
P
A
Y
L
E
R
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
I239
T
S
F
S
I
S
S
I
L
S
R
S
E
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
Sea Urchin
Strong. purpuratus
Q26656
405
44721
T123
T
R
H
P
L
S
A
T
V
P
G
L
G
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
91.1
N.A.
92.9
25.5
N.A.
46.7
57.5
27.1
22.5
N.A.
21.4
N.A.
26
25.6
Protein Similarity:
100
100
99.3
93.6
N.A.
95
33.8
N.A.
55.2
65.6
37.9
33
N.A.
28.2
N.A.
36.6
36.5
P-Site Identity:
100
100
100
93.3
N.A.
73.3
33.3
N.A.
13.3
20
13.3
13.3
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
33.3
N.A.
26.6
40
26.6
13.3
N.A.
40
N.A.
0
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
54
8
16
8
54
8
0
8
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
0
0
0
8
8
16
8
% E
% Phe:
0
0
8
0
8
8
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
47
8
39
0
0
39
0
0
0
8
0
8
39
8
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
8
0
8
0
47
0
16
54
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
8
8
54
8
24
16
0
8
39
16
39
8
8
% P
% Gln:
0
0
16
8
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
8
8
8
0
0
0
0
0
0
16
0
16
16
0
% R
% Ser:
39
16
0
8
8
16
16
39
8
16
8
8
0
0
47
% S
% Thr:
31
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
39
8
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _