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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLX2 All Species: 23.33
Human Site: S51 Identified Species: 42.78
UniProt: O43763 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43763 NP_057254.1 284 30251 S51 H G E N G A F S G G Y H G A S
Chimpanzee Pan troglodytes XP_001161223 284 30206 S51 H G E S G A F S G G Y H G A S
Rhesus Macaque Macaca mulatta XP_001110250 284 30204 S51 H G E S G A F S G G Y H G A S
Dog Lupus familis XP_855075 284 30159 S51 H G E S A A F S G G F H G T S
Cat Felis silvestris
Mouse Mus musculus Q61663 284 30342 S51 H G E S A A F S S G F H G A S
Rat Rattus norvegicus O88181 384 41445 Q84 H L V T D G P Q H H H H L H H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511680 344 37696 S52 Y G L G C I V S G A Y N T M T
Chicken Gallus gallus O93367 297 32351 R63 A A F L G G P R G G A P Y P A
Frog Xenopus laevis Q8JJ64 306 34004 T89 P G W W Y S Y T L A H G G H T
Zebra Danio Brachydanio rerio Q504H8 297 33069 N56 L S Q V G E I N F P R F E L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEI9 592 62591 T225 G G G G G K S T T G S N G F T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P56407 147 17231
Sea Urchin Strong. purpuratus Q26656 405 44721 E109 M S S N G Y S E G P I Y G S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.9 91.1 N.A. 92.9 25.5 N.A. 46.7 57.5 27.1 22.5 N.A. 21.4 N.A. 26 25.6
Protein Similarity: 100 100 99.3 93.6 N.A. 95 33.8 N.A. 55.2 65.6 37.9 33 N.A. 28.2 N.A. 36.6 36.5
P-Site Identity: 100 93.3 93.3 73.3 N.A. 73.3 13.3 N.A. 26.6 20 13.3 6.6 N.A. 26.6 N.A. 0 26.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 20 N.A. 46.6 26.6 46.6 20 N.A. 46.6 N.A. 0 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 16 39 0 0 0 16 8 0 0 31 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 39 0 0 8 0 8 0 0 0 0 8 0 0 % E
% Phe: 0 0 8 0 0 0 39 0 8 0 16 8 0 8 0 % F
% Gly: 8 62 8 16 54 16 0 0 54 54 0 8 62 0 0 % G
% His: 47 0 0 0 0 0 0 0 8 8 16 47 0 16 8 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 8 8 0 0 0 0 8 0 0 0 8 8 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 16 0 0 0 8 0 0 0 16 0 0 0 % N
% Pro: 8 0 0 0 0 0 16 0 0 16 0 8 0 8 8 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % R
% Ser: 0 16 8 31 0 8 16 47 8 0 8 0 0 8 39 % S
% Thr: 0 0 0 8 0 0 0 16 8 0 0 0 8 8 31 % T
% Val: 0 0 8 8 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 8 8 0 0 0 31 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _