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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLX2
All Species:
28.18
Human Site:
S167
Identified Species:
51.67
UniProt:
O43763
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43763
NP_057254.1
284
30251
S167
P
R
T
S
F
S
R
S
Q
V
L
E
L
E
R
Chimpanzee
Pan troglodytes
XP_001161223
284
30206
S167
P
R
T
S
F
S
R
S
Q
V
L
E
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001110250
284
30204
S167
P
R
T
S
F
S
R
S
Q
V
L
E
L
E
R
Dog
Lupus familis
XP_855075
284
30159
S167
P
R
T
S
F
S
R
S
Q
V
L
E
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61663
284
30342
S167
P
R
T
S
F
S
R
S
Q
V
L
E
L
E
R
Rat
Rattus norvegicus
O88181
384
41445
H239
A
R
T
A
F
S
D
H
Q
L
N
Q
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511680
344
37696
L220
P
R
T
S
F
T
R
L
Q
I
C
E
L
E
K
Chicken
Gallus gallus
O93367
297
32351
V182
P
R
T
S
F
S
R
V
Q
I
C
E
L
E
K
Frog
Xenopus laevis
Q8JJ64
306
34004
S188
T
R
T
V
F
S
R
S
Q
V
F
Q
L
E
S
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
S180
T
R
T
V
F
S
R
S
Q
V
F
Q
L
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
A478
T
R
T
V
F
S
R
A
Q
V
F
Q
L
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P56407
147
17231
E59
S
S
L
D
Q
A
K
E
S
P
I
E
K
C
Q
Sea Urchin
Strong. purpuratus
Q26656
405
44721
S263
T
R
T
V
F
S
R
S
Q
V
F
Q
L
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
91.1
N.A.
92.9
25.5
N.A.
46.7
57.5
27.1
22.5
N.A.
21.4
N.A.
26
25.6
Protein Similarity:
100
100
99.3
93.6
N.A.
95
33.8
N.A.
55.2
65.6
37.9
33
N.A.
28.2
N.A.
36.6
36.5
P-Site Identity:
100
100
100
100
N.A.
100
53.3
N.A.
66.6
73.3
66.6
66.6
N.A.
60
N.A.
6.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
86.6
86.6
73.3
73.3
N.A.
73.3
N.A.
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
62
0
93
0
% E
% Phe:
0
0
0
0
93
0
0
0
0
0
31
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
16
% K
% Leu:
0
0
8
0
0
0
0
8
0
8
39
0
93
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
54
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
93
0
0
39
0
0
8
% Q
% Arg:
0
93
0
0
0
0
85
0
0
0
0
0
0
0
47
% R
% Ser:
8
8
0
54
0
85
0
62
8
0
0
0
0
0
31
% S
% Thr:
31
0
93
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
31
0
0
0
8
0
70
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _