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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNGR1
All Species:
15.15
Human Site:
S189
Identified Species:
41.67
UniProt:
O43759
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43759
NP_004702.2
233
25456
S189
S
Q
D
Y
M
D
P
S
Q
D
S
S
M
P
Y
Chimpanzee
Pan troglodytes
NP_001131135
191
21031
R148
N
E
G
T
D
A
A
R
A
A
I
A
F
S
F
Rhesus Macaque
Macaca mulatta
XP_001107757
224
24760
Y181
V
D
D
F
I
Q
N
Y
V
D
P
T
P
D
P
Dog
Lupus familis
XP_852509
335
36374
S290
S
Q
D
Y
M
D
P
S
Q
D
S
S
M
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
O55100
234
25634
S189
S
Q
D
Y
M
D
P
S
Q
D
S
S
M
P
Y
Rat
Rattus norvegicus
Q62876
234
25650
S189
S
Q
D
Y
M
D
P
S
Q
D
S
S
M
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007835
230
25156
F186
S
L
F
A
T
D
Q
F
A
T
D
P
N
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001006067
223
24637
F180
L
G
S
S
S
S
L
F
S
Q
D
Y
T
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O76735
247
26774
F190
E
P
N
Y
D
E
H
F
G
Q
V
S
T
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.3
49.7
62
N.A.
94
93.1
N.A.
N.A.
53.6
N.A.
65.2
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
100
78.5
63.5
65
N.A.
95.3
94.8
N.A.
N.A.
67.3
N.A.
76.8
N.A.
N.A.
N.A.
46.5
N.A.
P-Site Identity:
100
0
13.3
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
33.3
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
12
0
23
12
0
12
0
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
56
0
23
56
0
0
0
56
23
0
0
34
0
% D
% Glu:
12
12
0
0
0
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
12
12
0
0
0
34
0
0
0
0
12
0
12
% F
% Gly:
0
12
12
0
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
45
0
0
0
0
0
0
0
45
0
0
% M
% Asn:
12
0
12
0
0
0
12
0
0
0
0
0
12
0
0
% N
% Pro:
0
12
0
0
0
0
45
0
0
0
12
12
12
45
23
% P
% Gln:
0
45
0
0
0
12
12
0
45
23
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
56
0
12
12
12
12
0
45
12
0
45
56
0
12
0
% S
% Thr:
0
0
0
12
12
0
0
0
0
12
0
12
23
0
0
% T
% Val:
12
0
0
0
0
0
0
0
12
0
12
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
56
0
0
0
12
0
0
0
12
0
0
45
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _