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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB2
All Species:
48.48
Human Site:
Y242
Identified Species:
82.05
UniProt:
O43741
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43741
NP_005390.1
272
30302
Y242
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
S
Chimpanzee
Pan troglodytes
XP_513749
272
30341
Y242
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
S
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
Y242
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
S
Dog
Lupus familis
XP_850153
272
30208
Y242
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAM0
271
30191
Y241
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
S
Rat
Rattus norvegicus
Q9QZH4
271
30209
Y241
H
V
M
L
N
H
L
Y
A
L
S
T
K
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
Y255
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
S
Chicken
Gallus gallus
NP_001038127
274
30623
Y244
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
G
Frog
Xenopus laevis
NP_001080680
271
30218
Y241
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
G
Zebra Danio
Brachydanio rerio
NP_001124105
269
29655
Y238
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393160
283
31818
Y253
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
Y248
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
Q257
I
L
N
H
L
Y
M
Q
K
G
K
S
G
P
S
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
V382
H
V
V
L
N
H
L
V
T
S
S
I
K
H
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.7
N.A.
97
97
N.A.
75
89.7
84.5
75
N.A.
N.A.
51.5
N.A.
51.2
Protein Similarity:
100
99.6
99.6
95.2
N.A.
98.1
98.1
N.A.
82.1
94.8
91.5
84.1
N.A.
N.A.
65.7
N.A.
63.8
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
100
93.3
93.3
93.3
N.A.
N.A.
100
N.A.
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
100
93.3
93.3
93.3
N.A.
N.A.
100
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
86
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
29
% G
% His:
93
0
0
8
0
93
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
86
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
8
0
93
0
0
% K
% Leu:
0
8
0
93
8
0
93
0
0
86
0
0
0
0
0
% L
% Met:
0
0
86
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
93
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
93
8
0
0
65
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% T
% Val:
0
93
8
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
86
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _