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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB2
All Species:
33.03
Human Site:
Y194
Identified Species:
55.9
UniProt:
O43741
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43741
NP_005390.1
272
30302
Y194
G
P
Y
G
Q
E
M
Y
A
F
R
S
E
E
R
Chimpanzee
Pan troglodytes
XP_513749
272
30341
Y194
G
P
Y
G
Q
E
M
Y
T
F
R
S
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
Y194
G
P
Y
G
Q
E
M
Y
V
F
R
S
E
E
R
Dog
Lupus familis
XP_850153
272
30208
Y194
G
P
Y
G
Q
E
M
Y
V
F
R
S
E
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAM0
271
30191
Y193
G
P
Y
G
Q
E
M
Y
V
F
R
S
E
E
R
Rat
Rattus norvegicus
Q9QZH4
271
30209
Y193
G
P
Y
G
Q
E
M
Y
V
F
R
S
E
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
Y207
G
L
Y
G
Q
E
M
Y
V
F
R
S
E
E
R
Chicken
Gallus gallus
NP_001038127
274
30623
Y196
G
P
Y
G
Q
E
M
Y
V
Y
R
P
E
E
R
Frog
Xenopus laevis
NP_001080680
271
30218
Y193
G
L
Y
G
Q
E
L
Y
A
Y
K
P
E
E
R
Zebra Danio
Brachydanio rerio
NP_001124105
269
29655
F192
Y
G
Q
E
V
Y
M
F
R
P
E
E
R
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393160
283
31818
P205
T
E
Y
G
Q
E
I
P
P
H
K
P
W
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
I199
P
G
D
Y
N
Q
D
I
P
S
Q
E
L
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
L207
P
E
N
S
Y
S
N
L
L
L
G
A
E
D
Y
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
D284
L
Q
I
G
K
D
P
D
D
F
G
D
G
Y
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.7
N.A.
97
97
N.A.
75
89.7
84.5
75
N.A.
N.A.
51.5
N.A.
51.2
Protein Similarity:
100
99.6
99.6
95.2
N.A.
98.1
98.1
N.A.
82.1
94.8
91.5
84.1
N.A.
N.A.
65.7
N.A.
63.8
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
80
66.6
6.6
N.A.
N.A.
33.3
N.A.
0
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
20
N.A.
N.A.
53.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
8
8
8
0
0
8
0
8
0
% D
% Glu:
0
15
0
8
0
72
0
0
0
0
8
15
72
72
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
58
0
0
0
8
0
% F
% Gly:
65
15
0
79
0
0
0
0
0
0
15
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
15
0
0
0
15
% K
% Leu:
8
15
0
0
0
0
8
8
8
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
65
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
15
50
0
0
0
0
8
8
15
8
0
22
0
0
0
% P
% Gln:
0
8
8
0
72
8
0
0
0
0
8
0
0
8
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
58
0
8
0
65
% R
% Ser:
0
0
0
8
0
8
0
0
0
8
0
50
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% T
% Val:
0
0
0
0
8
0
0
0
43
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
72
8
8
8
0
65
0
15
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _