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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB2
All Species:
43.03
Human Site:
T148
Identified Species:
72.82
UniProt:
O43741
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43741
NP_005390.1
272
30302
T148
V
V
T
S
Q
L
G
T
I
N
N
L
I
H
V
Chimpanzee
Pan troglodytes
XP_513749
272
30341
T148
V
V
T
S
Q
L
G
T
I
N
N
L
I
H
V
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
T148
V
V
T
S
Q
L
G
T
I
N
N
L
I
H
V
Dog
Lupus familis
XP_850153
272
30208
T148
V
V
T
S
Q
L
G
T
I
N
N
L
I
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAM0
271
30191
T147
V
V
T
S
Q
L
G
T
I
N
N
L
I
H
V
Rat
Rattus norvegicus
Q9QZH4
271
30209
T147
V
V
T
S
Q
L
G
T
I
N
N
L
I
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
T161
M
V
T
S
Q
L
G
T
I
N
N
W
I
Q
V
Chicken
Gallus gallus
NP_001038127
274
30623
T150
V
V
T
S
Q
M
G
T
I
N
N
L
I
H
V
Frog
Xenopus laevis
NP_001080680
271
30218
T147
V
V
T
S
Q
L
G
T
I
N
N
L
I
H
V
Zebra Danio
Brachydanio rerio
NP_001124105
269
29655
T146
V
I
T
S
Q
L
G
T
I
N
N
L
I
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393160
283
31818
K159
W
R
H
D
P
D
I
K
I
V
D
N
G
M
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
T153
L
Q
S
N
T
F
G
T
V
N
N
F
I
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
A161
V
D
G
Q
W
R
H
A
P
E
L
P
L
A
R
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
N238
T
A
T
D
Q
M
G
N
F
V
N
Y
I
E
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.7
N.A.
97
97
N.A.
75
89.7
84.5
75
N.A.
N.A.
51.5
N.A.
51.2
Protein Similarity:
100
99.6
99.6
95.2
N.A.
98.1
98.1
N.A.
82.1
94.8
91.5
84.1
N.A.
N.A.
65.7
N.A.
63.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
93.3
100
86.6
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
100
100
93.3
N.A.
N.A.
13.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
15
0
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
86
0
0
0
0
0
8
0
8
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
0
0
58
0
% H
% Ile:
0
8
0
0
0
0
8
0
79
0
0
0
86
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
65
0
0
0
0
8
65
8
0
0
% L
% Met:
8
0
0
0
0
15
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
79
86
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% P
% Gln:
0
8
0
8
79
0
0
0
0
0
0
0
0
15
0
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
8
72
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
8
0
79
0
8
0
0
79
0
0
0
0
0
0
0
% T
% Val:
72
65
0
0
0
0
0
0
8
15
0
0
0
0
86
% V
% Trp:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _