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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAB2 All Species: 26.67
Human Site: S51 Identified Species: 45.13
UniProt: O43741 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43741 NP_005390.1 272 30302 S51 S V F S L P D S K L P G D K E
Chimpanzee Pan troglodytes XP_513749 272 30341 S51 N V F S L P D S K L P G D K E
Rhesus Macaque Macaca mulatta XP_001093423 272 30312 S51 S V F S L P D S K L P G D K E
Dog Lupus familis XP_850153 272 30208 P51 S V F S L P D P K L P G D K E
Cat Felis silvestris
Mouse Mus musculus Q6PAM0 271 30191 S50 S V F S L P D S K L P G D K E
Rat Rattus norvegicus Q9QZH4 271 30209 S50 S V F S L P D S K L P G D K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514296 285 32181 T64 P L R S L F Q T Q L P G D R D
Chicken Gallus gallus NP_001038127 274 30623 S53 S V F S S H D S K I P G D K E
Frog Xenopus laevis NP_001080680 271 30218 T50 D D P N I F S T Q E S K H P G
Zebra Danio Brachydanio rerio NP_001124105 269 29655 A49 T H G P E S K A A G D K D V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393160 283 31818 E58 V F Q S S H E E E E P Y F A K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797535 279 30846 L56 P A G R F R E L M R D D G P D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCY5 289 31974 F63 A T Q S P L M F A P Q V P V L
Baker's Yeast Sacchar. cerevisiae P34164 415 46386 P138 D R S G H S S P R E E G Q Q Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 99.6 93.7 N.A. 97 97 N.A. 75 89.7 84.5 75 N.A. N.A. 51.5 N.A. 51.2
Protein Similarity: 100 99.6 99.6 95.2 N.A. 98.1 98.1 N.A. 82.1 94.8 91.5 84.1 N.A. N.A. 65.7 N.A. 63.8
P-Site Identity: 100 93.3 100 93.3 N.A. 100 100 N.A. 40 80 0 6.6 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 73.3 86.6 26.6 20 N.A. N.A. 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 33.5 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. 47.7 39.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 8 15 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 0 0 0 0 50 0 0 0 15 8 65 0 15 % D
% Glu: 0 0 0 0 8 0 15 8 8 22 8 0 0 0 50 % E
% Phe: 0 8 50 0 8 15 0 8 0 0 0 0 8 0 0 % F
% Gly: 0 0 15 8 0 0 0 0 0 8 0 65 8 0 8 % G
% His: 0 8 0 0 8 15 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 50 0 0 15 0 50 8 % K
% Leu: 0 8 0 0 50 8 0 8 0 50 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 8 8 8 43 0 15 0 8 65 0 8 15 0 % P
% Gln: 0 0 15 0 0 0 8 0 15 0 8 0 8 8 8 % Q
% Arg: 0 8 8 8 0 8 0 0 8 8 0 0 0 8 0 % R
% Ser: 43 0 8 72 15 15 15 43 0 0 8 0 0 0 0 % S
% Thr: 8 8 0 0 0 0 0 15 0 0 0 0 0 0 0 % T
% Val: 8 50 0 0 0 0 0 0 0 0 0 8 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _