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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB2
All Species:
47.88
Human Site:
S108
Identified Species:
81.03
UniProt:
O43741
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43741
NP_005390.1
272
30302
S108
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Chimpanzee
Pan troglodytes
XP_513749
272
30341
S108
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
S108
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Dog
Lupus familis
XP_850153
272
30208
S108
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAM0
271
30191
S107
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Rat
Rattus norvegicus
Q9QZH4
271
30209
S107
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
S121
A
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Chicken
Gallus gallus
NP_001038127
274
30623
S110
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Frog
Xenopus laevis
NP_001080680
271
30218
S107
T
K
I
P
L
I
K
S
H
N
D
F
V
A
I
Zebra Danio
Brachydanio rerio
NP_001124105
269
29655
S106
S
K
I
P
L
N
K
S
H
N
D
F
V
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393160
283
31818
T115
K
Q
V
Y
I
S
G
T
F
T
G
W
K
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
S113
T
K
I
P
M
I
K
S
Q
G
D
F
T
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
S120
K
E
I
A
V
E
G
S
W
D
N
W
K
T
R
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
D195
K
M
I
G
L
I
P
D
S
D
N
N
G
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.6
93.7
N.A.
97
97
N.A.
75
89.7
84.5
75
N.A.
N.A.
51.5
N.A.
51.2
Protein Similarity:
100
99.6
99.6
95.2
N.A.
98.1
98.1
N.A.
82.1
94.8
91.5
84.1
N.A.
N.A.
65.7
N.A.
63.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
100
86.6
N.A.
N.A.
0
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
100
93.3
N.A.
N.A.
40
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
0
0
0
79
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
15
79
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
79
0
0
8
% F
% Gly:
0
0
0
8
0
0
15
0
0
8
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% H
% Ile:
0
0
93
0
8
79
0
0
0
0
0
0
0
0
79
% I
% Lys:
22
79
0
0
0
0
79
0
0
0
0
0
15
0
0
% K
% Leu:
0
0
0
0
79
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
72
15
8
0
0
0
% N
% Pro:
0
0
0
79
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
0
0
0
8
0
86
8
0
0
0
0
8
0
% S
% Thr:
65
0
0
0
0
0
0
8
0
8
0
0
8
15
0
% T
% Val:
0
0
8
0
8
0
0
0
0
0
0
0
72
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _