KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP10
All Species:
14.85
Human Site:
Y652
Identified Species:
27.22
UniProt:
O43572
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43572
NP_009133.2
662
73818
Y652
D
I
M
Q
Q
A
Q
Y
D
Q
P
L
E
K
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099682
643
71871
Y633
D
V
M
Q
Q
A
Q
Y
D
Q
P
L
E
K
S
Dog
Lupus familis
XP_851367
662
73924
Y652
D
V
M
Q
Q
A
Q
Y
D
Q
P
L
E
K
S
Cat
Felis silvestris
Mouse
Mus musculus
O88845
662
73613
H652
D
V
M
Q
Q
A
H
H
D
Q
P
L
E
K
S
Rat
Rattus norvegicus
NP_001108078
662
73756
H652
D
V
M
Q
Q
A
H
H
D
Q
P
L
E
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508501
708
79092
Y657
D
V
M
Q
Q
A
Q
Y
D
Q
P
L
E
K
S
Chicken
Gallus gallus
XP_415856
639
71234
C629
D
V
M
Q
Q
A
H
C
E
Q
R
L
E
K
G
Frog
Xenopus laevis
NP_001084758
636
71076
R626
D
V
M
Q
Q
A
Q
R
S
P
S
P
E
K
S
Zebra Danio
Brachydanio rerio
XP_695298
653
72913
H628
D
V
M
Q
Q
G
H
H
G
S
P
E
T
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609783
622
69650
T613
V
R
D
V
T
S
V
T
L
S
G
K
T
P
P
Honey Bee
Apis mellifera
XP_001122405
513
59382
L504
I
I
R
E
I
T
S
L
T
L
G
A
S
N
F
Nematode Worm
Caenorhab. elegans
Q10955
492
55905
S483
M
V
A
S
S
A
E
S
P
T
S
P
T
F
R
Sea Urchin
Strong. purpuratus
XP_001203361
588
65696
P579
A
G
E
D
I
P
S
P
T
A
A
K
P
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
94.7
N.A.
89.7
90.9
N.A.
78.2
80
70.6
66
N.A.
26.2
30.2
21.7
34.5
Protein Similarity:
100
N.A.
96
96.8
N.A.
94.2
95
N.A.
84
86.8
79.4
77.7
N.A.
44.5
48.3
37.9
54
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
80
80
N.A.
93.3
60
60
33.3
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
73.3
66.6
46.6
N.A.
6.6
13.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
70
0
0
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
70
0
8
8
0
0
0
0
47
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
0
0
8
0
8
0
0
8
62
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
8
0
0
0
8
0
0
8
0
16
0
0
8
8
% G
% His:
0
0
0
0
0
0
31
24
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
0
16
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
16
0
62
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
8
0
54
0
0
0
% L
% Met:
8
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
8
8
8
54
16
8
16
8
% P
% Gln:
0
0
0
70
70
0
39
0
0
54
0
0
0
0
8
% Q
% Arg:
0
8
8
0
0
0
0
8
0
0
8
0
0
0
8
% R
% Ser:
0
0
0
8
8
8
16
8
8
16
16
0
8
0
54
% S
% Thr:
0
0
0
0
8
8
0
8
16
8
0
0
24
0
0
% T
% Val:
8
70
0
8
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _