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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP10
All Species:
31.82
Human Site:
Y582
Identified Species:
58.33
UniProt:
O43572
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43572
NP_009133.2
662
73818
Y582
E
S
L
Y
Q
R
T
Y
A
G
K
M
T
F
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099682
643
71871
Y563
E
S
L
Y
Q
R
T
Y
A
G
K
M
T
F
G
Dog
Lupus familis
XP_851367
662
73924
Y582
E
S
L
Y
Q
R
T
Y
A
G
K
M
T
F
G
Cat
Felis silvestris
Mouse
Mus musculus
O88845
662
73613
Y582
E
S
L
Y
Q
R
T
Y
A
G
K
M
S
F
G
Rat
Rattus norvegicus
NP_001108078
662
73756
Y582
E
S
L
Y
Q
R
T
Y
A
G
K
M
S
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508501
708
79092
Y587
E
S
L
Y
Q
R
T
Y
A
G
K
M
T
F
G
Chicken
Gallus gallus
XP_415856
639
71234
Y559
E
S
L
Y
Q
R
T
Y
A
G
K
M
T
F
G
Frog
Xenopus laevis
NP_001084758
636
71076
Y556
E
S
L
Y
Q
R
T
Y
A
G
K
M
T
F
G
Zebra Danio
Brachydanio rerio
XP_695298
653
72913
G560
L
Y
Q
R
P
Y
A
G
R
M
T
F
G
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609783
622
69650
F545
V
G
A
L
K
F
G
F
V
N
S
L
G
R
Y
Honey Bee
Apis mellifera
XP_001122405
513
59382
W436
L
Y
D
P
D
S
L
W
K
R
N
K
Y
S
L
Nematode Worm
Caenorhab. elegans
Q10955
492
55905
R415
P
R
T
P
R
S
S
R
L
A
E
V
D
E
M
Sea Urchin
Strong. purpuratus
XP_001203361
588
65696
H511
M
M
F
G
K
M
D
H
L
G
Q
F
V
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
94.7
N.A.
89.7
90.9
N.A.
78.2
80
70.6
66
N.A.
26.2
30.2
21.7
34.5
Protein Similarity:
100
N.A.
96
96.8
N.A.
94.2
95
N.A.
84
86.8
79.4
77.7
N.A.
44.5
48.3
37.9
54
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
100
100
0
N.A.
0
0
0
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
100
0
N.A.
20
6.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
62
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
62
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% E
% Phe:
0
0
8
0
0
8
0
8
0
0
0
16
0
62
0
% F
% Gly:
0
8
0
8
0
0
8
8
0
70
0
0
16
0
62
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
16
0
0
0
8
0
62
8
0
8
0
% K
% Leu:
16
0
62
8
0
0
8
0
16
0
0
8
0
0
8
% L
% Met:
8
8
0
0
0
8
0
0
0
8
0
62
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
8
0
0
16
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
8
0
62
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
8
8
62
0
8
8
8
0
0
0
8
0
% R
% Ser:
0
62
0
0
0
16
8
0
0
0
8
0
16
8
0
% S
% Thr:
0
0
8
0
0
0
62
0
0
0
8
0
47
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
0
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
62
0
8
0
62
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _