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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP10
All Species:
12.42
Human Site:
T257
Identified Species:
22.78
UniProt:
O43572
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43572
NP_009133.2
662
73818
T257
L
E
M
A
R
A
G
T
H
Q
V
S
M
E
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099682
643
71871
S250
M
E
T
Q
E
S
S
S
T
L
T
V
A
S
R
Dog
Lupus familis
XP_851367
662
73924
M257
L
E
M
A
R
T
G
M
H
Q
V
S
M
E
T
Cat
Felis silvestris
Mouse
Mus musculus
O88845
662
73613
S257
R
E
V
A
R
T
G
S
H
Q
I
P
T
D
S
Rat
Rattus norvegicus
NP_001108078
662
73756
T257
H
E
V
A
R
T
G
T
H
Q
I
S
T
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508501
708
79092
E261
H
L
G
M
L
K
A
E
P
H
P
V
S
M
E
Chicken
Gallus gallus
XP_415856
639
71234
S251
E
S
S
K
L
T
V
S
N
R
N
S
P
S
S
Frog
Xenopus laevis
NP_001084758
636
71076
T250
H
V
T
S
A
K
N
T
P
T
H
T
G
F
T
Zebra Danio
Brachydanio rerio
XP_695298
653
72913
T251
S
E
T
P
T
R
Q
T
S
S
R
T
G
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609783
622
69650
Y241
A
I
A
I
Y
Q
K
Y
L
I
V
N
A
S
L
Honey Bee
Apis mellifera
XP_001122405
513
59382
N132
Q
C
D
M
T
Q
N
N
I
N
N
F
E
N
K
Nematode Worm
Caenorhab. elegans
Q10955
492
55905
F110
D
K
L
N
L
I
K
F
W
M
H
V
E
G
F
Sea Urchin
Strong. purpuratus
XP_001203361
588
65696
D206
H
N
S
W
K
E
V
D
P
R
T
A
V
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
94.7
N.A.
89.7
90.9
N.A.
78.2
80
70.6
66
N.A.
26.2
30.2
21.7
34.5
Protein Similarity:
100
N.A.
96
96.8
N.A.
94.2
95
N.A.
84
86.8
79.4
77.7
N.A.
44.5
48.3
37.9
54
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
40
53.3
N.A.
0
6.6
13.3
13.3
N.A.
6.6
0
0
6.6
P-Site Similarity:
100
N.A.
26.6
86.6
N.A.
73.3
80
N.A.
0
33.3
26.6
20
N.A.
13.3
0
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
31
8
8
8
0
0
0
0
8
16
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
8
0
0
0
0
0
16
0
% D
% Glu:
8
47
0
0
8
8
0
8
0
0
0
0
16
24
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
8
0
8
8
% F
% Gly:
0
0
8
0
0
0
31
0
0
0
0
0
16
8
0
% G
% His:
31
0
0
0
0
0
0
0
31
8
16
0
0
0
0
% H
% Ile:
0
8
0
8
0
8
0
0
8
8
16
0
0
0
0
% I
% Lys:
0
8
0
8
8
16
16
0
0
0
0
0
0
0
8
% K
% Leu:
16
8
8
0
24
0
0
0
8
8
0
0
0
0
8
% L
% Met:
8
0
16
16
0
0
0
8
0
8
0
0
16
8
0
% M
% Asn:
0
8
0
8
0
0
16
8
8
8
16
8
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
24
0
8
8
8
0
8
% P
% Gln:
8
0
0
8
0
16
8
0
0
31
0
0
0
0
0
% Q
% Arg:
8
0
0
0
31
8
0
0
0
16
8
0
0
0
16
% R
% Ser:
8
8
16
8
0
8
8
24
8
8
0
31
8
24
24
% S
% Thr:
0
0
24
0
16
31
0
31
8
8
16
16
16
8
24
% T
% Val:
0
8
16
0
0
0
16
0
0
0
24
24
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _