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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP10
All Species:
9.09
Human Site:
S220
Identified Species:
16.67
UniProt:
O43572
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43572
NP_009133.2
662
73818
S220
A
Q
L
F
M
T
H
S
E
G
I
D
L
N
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099682
643
71871
T213
L
N
N
R
T
N
S
T
Q
N
H
L
L
L
S
Dog
Lupus familis
XP_851367
662
73924
P220
A
Q
L
L
M
T
Q
P
E
G
I
D
L
N
N
Cat
Felis silvestris
Mouse
Mus musculus
O88845
662
73613
S220
A
P
L
L
V
T
Q
S
E
G
T
D
L
S
S
Rat
Rattus norvegicus
NP_001108078
662
73756
S220
A
P
L
L
L
T
Q
S
E
G
T
D
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508501
708
79092
T224
T
V
Q
L
L
V
T
T
S
K
G
T
D
L
N
Chicken
Gallus gallus
XP_415856
639
71234
V214
T
H
N
S
R
N
H
V
L
S
A
Q
E
R
D
Frog
Xenopus laevis
NP_001084758
636
71076
E213
T
S
A
S
N
H
L
E
T
K
Q
K
T
G
G
Zebra Danio
Brachydanio rerio
XP_695298
653
72913
H214
S
P
Q
D
T
N
S
H
S
G
A
L
M
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609783
622
69650
Y204
D
D
E
K
S
R
I
Y
A
E
T
N
K
Q
L
Honey Bee
Apis mellifera
XP_001122405
513
59382
L95
I
L
A
D
K
G
A
L
G
Y
F
I
Q
F
M
Nematode Worm
Caenorhab. elegans
Q10955
492
55905
K73
D
H
E
G
I
I
V
K
Q
K
P
Q
L
A
F
Sea Urchin
Strong. purpuratus
XP_001203361
588
65696
K169
S
P
S
R
S
P
Q
K
T
H
T
R
A
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
94.7
N.A.
89.7
90.9
N.A.
78.2
80
70.6
66
N.A.
26.2
30.2
21.7
34.5
Protein Similarity:
100
N.A.
96
96.8
N.A.
94.2
95
N.A.
84
86.8
79.4
77.7
N.A.
44.5
48.3
37.9
54
P-Site Identity:
100
N.A.
6.6
80
N.A.
53.3
53.3
N.A.
6.6
6.6
0
6.6
N.A.
0
0
6.6
0
P-Site Similarity:
100
N.A.
26.6
80
N.A.
73.3
73.3
N.A.
20
13.3
0
33.3
N.A.
6.6
0
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
16
0
0
0
8
0
8
0
16
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
8
0
16
0
0
0
0
0
0
0
31
8
0
8
% D
% Glu:
0
0
16
0
0
0
0
8
31
8
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
8
8
% F
% Gly:
0
0
0
8
0
8
0
0
8
39
8
0
0
8
8
% G
% His:
0
16
0
0
0
8
16
8
0
8
8
0
0
0
8
% H
% Ile:
8
0
0
0
8
8
8
0
0
0
16
8
0
0
0
% I
% Lys:
0
0
0
8
8
0
0
16
0
24
0
8
8
0
0
% K
% Leu:
8
8
31
31
16
0
8
8
8
0
0
16
47
16
8
% L
% Met:
0
0
0
0
16
0
0
0
0
0
0
0
8
8
8
% M
% Asn:
0
8
16
0
8
24
0
0
0
8
0
8
0
16
24
% N
% Pro:
0
31
0
0
0
8
0
8
0
0
8
0
0
0
0
% P
% Gln:
0
16
16
0
0
0
31
0
16
0
8
16
8
8
0
% Q
% Arg:
0
0
0
16
8
8
0
0
0
0
0
8
0
8
0
% R
% Ser:
16
8
8
16
16
0
16
24
16
8
0
0
0
24
31
% S
% Thr:
24
0
0
0
16
31
8
16
16
0
31
8
8
0
0
% T
% Val:
0
8
0
0
8
8
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _