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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP10
All Species:
18.18
Human Site:
S163
Identified Species:
33.33
UniProt:
O43572
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43572
NP_009133.2
662
73818
S163
L
E
A
E
S
F
H
S
T
T
W
S
R
I
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099682
643
71871
N156
R
I
R
A
H
S
L
N
T
V
K
Q
S
S
L
Dog
Lupus familis
XP_851367
662
73924
S163
L
E
A
E
S
F
H
S
T
T
W
S
R
I
R
Cat
Felis silvestris
Mouse
Mus musculus
O88845
662
73613
S163
L
E
A
E
S
F
H
S
T
T
W
S
R
I
R
Rat
Rattus norvegicus
NP_001108078
662
73756
S163
L
E
A
E
S
F
H
S
T
T
W
S
R
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508501
708
79092
S167
L
E
A
E
S
F
H
S
T
T
W
S
R
I
R
Chicken
Gallus gallus
XP_415856
639
71234
Q157
H
S
L
N
T
V
K
Q
S
S
L
A
E
P
V
Frog
Xenopus laevis
NP_001084758
636
71076
V156
R
A
F
S
L
N
T
V
K
H
S
S
L
A
E
Zebra Danio
Brachydanio rerio
XP_695298
653
72913
K157
A
H
S
L
N
S
V
K
H
S
T
L
A
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609783
622
69650
N147
K
F
Y
L
D
I
E
N
F
K
R
A
A
L
T
Honey Bee
Apis mellifera
XP_001122405
513
59382
G38
S
S
S
G
K
L
F
G
D
V
F
N
S
G
S
Nematode Worm
Caenorhab. elegans
Q10955
492
55905
Q16
R
R
K
K
D
K
E
Q
N
G
H
T
A
T
S
Sea Urchin
Strong. purpuratus
XP_001203361
588
65696
C112
I
N
S
K
E
T
M
C
N
S
S
E
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.4
94.7
N.A.
89.7
90.9
N.A.
78.2
80
70.6
66
N.A.
26.2
30.2
21.7
34.5
Protein Similarity:
100
N.A.
96
96.8
N.A.
94.2
95
N.A.
84
86.8
79.4
77.7
N.A.
44.5
48.3
37.9
54
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
100
0
6.6
0
N.A.
0
0
0
0
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
100
26.6
6.6
20
N.A.
20
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
39
8
0
0
0
0
0
0
0
16
24
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
39
0
39
8
0
16
0
0
0
0
8
8
8
8
% E
% Phe:
0
8
8
0
0
39
8
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
8
0
0
0
8
0
% G
% His:
8
8
0
0
8
0
39
0
8
8
8
0
0
0
0
% H
% Ile:
8
8
0
0
0
8
0
0
0
0
0
0
0
39
0
% I
% Lys:
8
0
8
16
8
8
8
8
8
8
8
0
0
0
0
% K
% Leu:
39
0
8
16
8
8
8
0
0
0
8
8
8
8
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
8
0
16
16
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
16
% P
% Gln:
0
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% Q
% Arg:
24
8
8
0
0
0
0
0
0
0
8
0
39
0
39
% R
% Ser:
8
16
24
8
39
16
0
39
8
24
16
47
16
16
16
% S
% Thr:
0
0
0
0
8
8
8
0
47
39
8
8
0
8
8
% T
% Val:
0
0
0
0
0
8
8
8
0
16
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _