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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGAM
All Species:
8.79
Human Site:
T546
Identified Species:
19.33
UniProt:
O43451
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43451
NP_004659.2
1857
209852
T546
G
S
V
S
G
C
S
T
N
N
L
N
N
P
P
Chimpanzee
Pan troglodytes
XP_519434
1861
212306
L517
H
L
L
F
A
R
T
L
C
M
D
T
E
F
H
Rhesus Macaque
Macaca mulatta
XP_001083672
2150
242962
T555
G
S
V
S
G
C
S
T
N
N
L
N
N
P
P
Dog
Lupus familis
XP_532746
1924
216856
T611
G
S
I
S
G
C
S
T
S
H
L
N
Y
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P70699
953
106229
Rat
Rattus norvegicus
P23739
1841
210332
L533
L
N
L
K
G
V
L
L
I
V
L
N
Y
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519457
586
66593
Chicken
Gallus gallus
XP_422811
1809
205701
P513
L
N
Y
P
P
F
T
P
N
I
V
D
K
L
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919135
1317
150404
K70
L
A
T
E
R
A
S
K
E
V
F
G
T
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797271
1782
203460
D522
A
F
D
G
I
W
I
D
M
N
E
P
A
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S7Y7
915
102380
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.6
79
82.3
N.A.
25.6
57.1
N.A.
24.3
61.2
N.A.
42.9
N.A.
N.A.
N.A.
N.A.
41.9
Protein Similarity:
100
77.1
82.4
88.8
N.A.
34.5
72.3
N.A.
27.2
75.2
N.A.
54.3
N.A.
N.A.
N.A.
N.A.
58.8
P-Site Identity:
100
0
100
73.3
N.A.
0
33.3
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
0
46.6
N.A.
0
33.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
10
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
28
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
10
0
10
0
10
0
0
% E
% Phe:
0
10
0
10
0
10
0
0
0
0
10
0
0
10
10
% F
% Gly:
28
0
0
10
37
0
0
0
0
0
0
10
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% H
% Ile:
0
0
10
0
10
0
10
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
10
0
0
0
0
10
0
0
% K
% Leu:
28
10
19
0
0
0
10
19
0
0
37
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% M
% Asn:
0
19
0
0
0
0
0
0
28
28
0
37
19
10
0
% N
% Pro:
0
0
0
10
10
0
0
10
0
0
0
10
0
37
37
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
28
0
28
0
0
37
0
10
0
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
19
28
0
0
0
10
10
0
0
% T
% Val:
0
0
19
0
0
10
0
0
0
19
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _