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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBX1 All Species: 5.76
Human Site: S81 Identified Species: 11.52
UniProt: O43435 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43435 NP_005983.1 398 43133 S81 P A A G A A T S A A A E P E G
Chimpanzee Pan troglodytes XP_514982 793 83801 A385 F A P A A G A A T S A A A E P
Rhesus Macaque Macaca mulatta XP_001117884 385 42153 Q80 P L W E E F N Q L G T E M I V
Dog Lupus familis XP_850266 325 36336 L44 D P A K L R R L L G S P A G M
Cat Felis silvestris
Mouse Mus musculus P70323 479 51650 E76 G S S A A E S E G P G A S R A
Rat Rattus norvegicus NP_001101792 480 51756 S76 A S S S A A E S E G P G A S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8UW76 440 48669 P78 P S A L C T E P L I P T T P I
Frog Xenopus laevis Q8AX98 463 51272 T85 S S S C A S S T P G S G S T G
Zebra Danio Brachydanio rerio Q8AXX2 460 51532 Q76 N S A Q A P A Q G D S G T S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24432 972 102538 T292 H H L G S A Y T T A E D V V L
Honey Bee Apis mellifera XP_624689 391 43181 P79 H H H G D H H P A E N G A N S
Nematode Worm Caenorhab. elegans Q19691 423 46979 E80 Q F S Q C G T E M V I T K S G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43 55.7 57.2 N.A. 68.6 69.3 N.A. N.A. 37.9 60 55.2 N.A. 20.5 41.7 36.4 N.A.
Protein Similarity: 100 44.3 66.8 62 N.A. 72.2 72.9 N.A. N.A. 49.7 67.1 63.4 N.A. 27.8 50.2 50.8 N.A.
P-Site Identity: 100 26.6 13.3 6.6 N.A. 6.6 20 N.A. N.A. 13.3 13.3 13.3 N.A. 20 13.3 13.3 N.A.
P-Site Similarity: 100 40 13.3 13.3 N.A. 26.6 33.3 N.A. N.A. 20 53.3 26.6 N.A. 40 13.3 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 34 17 50 25 17 9 17 17 17 17 34 0 9 % A
% Cys: 0 0 0 9 17 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 0 0 0 9 0 9 0 0 0 % D
% Glu: 0 0 0 9 9 9 17 17 9 9 9 17 0 17 0 % E
% Phe: 9 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 25 0 17 0 0 17 34 9 34 0 9 25 % G
% His: 17 17 9 0 0 9 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 9 0 0 9 9 % I
% Lys: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 9 9 9 9 0 0 9 25 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 9 % M
% Asn: 9 0 0 0 0 0 9 0 0 0 9 0 0 9 9 % N
% Pro: 25 9 9 0 0 9 0 17 9 9 17 9 9 9 9 % P
% Gln: 9 0 0 17 0 0 0 17 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 9 0 0 0 0 0 0 9 9 % R
% Ser: 9 42 34 9 9 9 17 17 0 9 25 0 17 25 9 % S
% Thr: 0 0 0 0 0 9 17 17 17 0 9 17 17 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 0 9 9 9 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _