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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX1
All Species:
34.24
Human Site:
S199
Identified Species:
68.48
UniProt:
O43435
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43435
NP_005983.1
398
43133
S199
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Chimpanzee
Pan troglodytes
XP_514982
793
83801
S497
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Rhesus Macaque
Macaca mulatta
XP_001117884
385
42153
F196
M
H
R
Y
Q
P
R
F
H
V
V
F
V
D
P
Dog
Lupus familis
XP_850266
325
36336
S156
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Cat
Felis silvestris
Mouse
Mus musculus
P70323
479
51650
S188
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Rat
Rattus norvegicus
NP_001101792
480
51756
S189
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8UW76
440
48669
I214
L
D
Q
H
G
H
I
I
L
N
S
M
H
K
Y
Frog
Xenopus laevis
Q8AX98
463
51272
S199
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Zebra Danio
Brachydanio rerio
Q8AXX2
460
51532
S196
R
V
H
Y
H
P
D
S
P
A
K
G
A
Q
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
S415
R
M
Y
I
H
P
D
S
P
T
T
G
E
Q
W
Honey Bee
Apis mellifera
XP_624689
391
43181
S193
R
I
H
V
H
P
D
S
P
A
S
G
A
H
W
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
M202
C
A
D
R
H
N
L
M
Y
S
T
F
R
T
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43
55.7
57.2
N.A.
68.6
69.3
N.A.
N.A.
37.9
60
55.2
N.A.
20.5
41.7
36.4
N.A.
Protein Similarity:
100
44.3
66.8
62
N.A.
72.2
72.9
N.A.
N.A.
49.7
67.1
63.4
N.A.
27.8
50.2
50.8
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
0
100
100
N.A.
60
73.3
6.6
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
20
100
100
N.A.
73.3
80
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
67
0
0
67
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
75
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
17
0
0
9
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
0
75
0
0
0
% G
% His:
0
9
67
9
84
9
0
0
9
0
0
0
9
9
0
% H
% Ile:
0
9
0
9
0
0
9
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
59
0
0
9
0
% K
% Leu:
9
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% L
% Met:
9
9
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
84
0
0
75
0
0
0
0
0
9
% P
% Gln:
0
0
9
0
9
0
0
0
0
0
0
0
0
67
0
% Q
% Arg:
75
0
9
9
0
0
9
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
0
0
0
0
0
75
0
9
17
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
17
0
0
9
0
% T
% Val:
0
59
0
9
0
0
0
0
0
9
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
75
% W
% Tyr:
0
0
9
67
0
0
0
0
9
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _