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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASA4
All Species:
17.27
Human Site:
Y593
Identified Species:
38
UniProt:
O43374
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43374
NP_008920.4
803
90458
Y593
S
S
S
F
K
K
L
Y
F
S
L
T
T
E
A
Chimpanzee
Pan troglodytes
XP_001156716
496
54819
A297
T
T
E
A
L
S
F
A
K
T
P
S
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001114645
802
88623
Y592
S
S
S
F
K
K
L
Y
F
F
L
T
T
E
A
Dog
Lupus familis
XP_546937
1108
121874
A851
T
T
A
V
G
K
I
A
T
S
S
A
N
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFQ7
802
90042
Y592
S
S
S
F
K
K
L
Y
F
S
L
T
T
E
A
Rat
Rattus norvegicus
Q9QYJ2
834
96002
W602
M
K
N
F
K
K
R
W
F
R
L
T
N
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514348
437
48786
S238
S
L
T
S
E
A
L
S
F
A
K
T
P
S
S
Chicken
Gallus gallus
XP_415761
763
85148
P563
G
E
G
W
P
C
A
P
R
A
A
V
V
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092921
800
91655
Y590
T
S
P
F
K
K
Y
Y
V
T
L
S
K
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48423
1163
132069
F869
N
S
I
R
M
Q
Y
F
H
P
S
A
F
V
S
Honey Bee
Apis mellifera
XP_395469
952
108478
Y623
R
K
N
F
K
Q
R
Y
F
K
L
T
T
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.7
50.8
50.9
N.A.
86.3
30.9
N.A.
39.4
59.6
N.A.
62
N.A.
20.2
27.7
N.A.
N.A.
Protein Similarity:
100
59.9
59.6
59.1
N.A.
90.7
49
N.A.
45.2
73
N.A.
77
N.A.
35.8
45.5
N.A.
N.A.
P-Site Identity:
100
0
93.3
13.3
N.A.
100
40
N.A.
26.6
0
N.A.
40
N.A.
6.6
46.6
N.A.
N.A.
P-Site Similarity:
100
40
93.3
40
N.A.
100
53.3
N.A.
53.3
20
N.A.
66.6
N.A.
33.3
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
10
19
0
19
10
19
0
10
28
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% D
% Glu:
0
10
10
0
10
0
0
0
0
0
0
0
0
28
19
% E
% Phe:
0
0
0
55
0
0
10
10
55
10
0
0
10
0
0
% F
% Gly:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
19
0
0
55
55
0
0
10
10
10
0
10
19
10
% K
% Leu:
0
10
0
0
10
0
37
0
0
0
55
0
0
0
10
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
19
0
0
0
0
0
0
0
0
0
19
0
0
% N
% Pro:
0
0
10
0
10
0
0
10
0
10
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
19
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
0
10
0
0
19
0
10
10
0
0
0
0
0
% R
% Ser:
37
46
28
10
0
10
0
10
0
28
19
19
10
10
19
% S
% Thr:
28
19
10
0
0
0
0
0
10
19
0
55
37
0
10
% T
% Val:
0
0
0
10
0
0
0
0
10
0
0
10
10
10
0
% V
% Trp:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
19
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _