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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RASA4 All Species: 10.91
Human Site: S612 Identified Species: 24
UniProt: O43374 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43374 NP_008920.4 803 90458 S612 K T P S S K K S A L I K L A N
Chimpanzee Pan troglodytes XP_001156716 496 54819 A316 K L A N I R A A E K V E E K S
Rhesus Macaque Macaca mulatta XP_001114645 802 88623 S611 K T P S S K K S A L I K L A N
Dog Lupus familis XP_546937 1108 121874 V870 N R L R R R A V C L A S S S S
Cat Felis silvestris
Mouse Mus musculus Q6PFQ7 802 90042 S611 K T S S S K K S T F I K L A S
Rat Rattus norvegicus Q9QYJ2 834 96002 L621 K S K G D Q P L C N I P I E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514348 437 48786 R257 F I P L A R I R A A E K V E E
Chicken Gallus gallus XP_415761 763 85148 G582 V H K T R G K G P L L A S A S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092921 800 91655 S609 R T L H S K K S S S I S L P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48423 1163 132069 N888 C C G R S D E N S P G C K K V
Honey Bee Apis mellifera XP_395469 952 108478 L642 K T K G K E P L C K I P L E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.7 50.8 50.9 N.A. 86.3 30.9 N.A. 39.4 59.6 N.A. 62 N.A. 20.2 27.7 N.A. N.A.
Protein Similarity: 100 59.9 59.6 59.1 N.A. 90.7 49 N.A. 45.2 73 N.A. 77 N.A. 35.8 45.5 N.A. N.A.
P-Site Identity: 100 6.6 100 6.6 N.A. 73.3 20 N.A. 20 20 N.A. 46.6 N.A. 6.6 26.6 N.A. N.A.
P-Site Similarity: 100 46.6 100 26.6 N.A. 80 40 N.A. 40 40 N.A. 60 N.A. 26.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 19 10 28 10 10 10 0 37 0 % A
% Cys: 10 10 0 0 0 0 0 0 28 0 0 10 0 0 0 % C
% Asp: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 10 0 10 0 10 10 10 28 19 % E
% Phe: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 19 0 10 0 10 0 0 10 0 0 0 0 % G
% His: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 0 10 0 0 0 55 0 10 0 0 % I
% Lys: 55 0 28 0 10 37 46 0 0 19 0 37 10 19 10 % K
% Leu: 0 10 19 10 0 0 0 19 0 37 10 0 46 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 0 0 10 0 10 0 0 0 0 28 % N
% Pro: 0 0 28 0 0 0 19 0 10 10 0 19 0 10 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 10 0 19 19 28 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 10 10 28 46 0 0 37 19 10 0 19 19 10 37 % S
% Thr: 0 46 0 10 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 10 0 0 10 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _