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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSI1 All Species: 11.82
Human Site: Y232 Identified Species: 21.67
UniProt: O43347 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43347 NP_002433.1 362 39125 Y232 T T Y A S R S Y T G L A P G Y
Chimpanzee Pan troglodytes XP_001162046 324 34904 A196 P P G T R G R A R G L P Y T M
Rhesus Macaque Macaca mulatta Q28521 320 34202 S192 E M A S A S S S Q R G R S G S
Dog Lupus familis XP_854252 351 38019 P220 G I G M L G Y P G F Q A T T Y
Cat Felis silvestris
Mouse Mus musculus Q61474 362 39101 Y232 T T Y A S R S Y T G L A P G Y
Rat Rattus norvegicus Q8K3P4 362 39115 Y232 T T Y A S R S Y T G L A P G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506312 349 37295 Y215 L G M G M L G Y P N F V A T Y
Chicken Gallus gallus Q5ZI72 301 33425 L173 E E P V K K L L E S R Y H Q I
Frog Xenopus laevis Q98SJ2 360 39210 P232 Q T W Q G Y S P Q G M W M P T
Zebra Danio Brachydanio rerio NP_001013534 330 35800 V202 S S R G R A R V M P Y G M D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVE5 369 40069 Y237 P A A A Y A A Y A A G R G Y S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 G218 S R D G Q R G G Y N G G G G G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 M373 P M M N P Q A M T D Y Y Q K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.3 30.1 96.6 N.A. 99.4 99.7 N.A. 65.4 31.4 32 80.9 N.A. 52.8 N.A. 28.1 N.A.
Protein Similarity: 100 75.4 44.4 96.6 N.A. 99.7 99.7 N.A. 72.3 45.8 45.5 87 N.A. 64.7 N.A. 42.5 N.A.
P-Site Identity: 100 13.3 13.3 13.3 N.A. 100 100 N.A. 13.3 0 20 0 N.A. 13.3 N.A. 13.3 N.A.
P-Site Similarity: 100 13.3 26.6 13.3 N.A. 100 100 N.A. 13.3 6.6 33.3 13.3 N.A. 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 16 31 8 16 16 8 8 8 0 31 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 16 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % F
% Gly: 8 8 16 24 8 16 16 8 8 39 24 16 16 39 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 8 8 0 0 0 0 0 0 0 8 0 % K
% Leu: 8 0 0 0 8 8 8 8 0 0 31 0 0 0 0 % L
% Met: 0 16 16 8 8 0 0 8 8 0 8 0 16 0 16 % M
% Asn: 0 0 0 8 0 0 0 0 0 16 0 0 0 0 0 % N
% Pro: 24 8 8 0 8 0 0 16 8 8 0 8 24 8 0 % P
% Gln: 8 0 0 8 8 8 0 0 16 0 8 0 8 8 0 % Q
% Arg: 0 8 8 0 16 31 16 0 8 8 8 16 0 0 0 % R
% Ser: 16 8 0 8 24 8 39 8 0 8 0 0 8 0 16 % S
% Thr: 24 31 0 8 0 0 0 0 31 0 0 0 8 24 8 % T
% Val: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 24 0 8 8 8 39 8 0 16 16 8 8 39 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _