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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI1
All Species:
27.58
Human Site:
Y128
Identified Species:
50.56
UniProt:
O43347
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43347
NP_002433.1
362
39125
Y128
T
V
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
G111
R
T
K
K
I
F
V
G
G
L
S
A
N
T
V
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
I107
A
H
L
T
V
K
K
I
F
V
G
G
I
K
E
Dog
Lupus familis
XP_854252
351
38019
Y128
T
V
E
D
V
K
Q
Y
F
E
Q
F
E
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61474
362
39101
Y128
T
V
E
D
V
K
H
Y
F
E
Q
F
G
K
V
Rat
Rattus norvegicus
Q8K3P4
362
39115
Y128
T
V
E
D
V
K
H
Y
F
E
Q
F
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
Y125
V
V
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
Chicken
Gallus gallus
Q5ZI72
301
33425
L88
A
A
S
V
E
K
V
L
E
L
K
E
H
K
L
Frog
Xenopus laevis
Q98SJ2
360
39210
Y133
G
E
T
E
L
K
E
Y
F
N
R
F
G
V
V
Zebra Danio
Brachydanio rerio
NP_001013534
330
35800
S117
K
I
F
V
G
G
L
S
V
N
T
T
I
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
Y137
T
L
E
D
V
K
S
Y
F
E
Q
F
G
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
Y133
T
E
D
M
L
T
E
Y
F
T
K
Y
G
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
F262
R
P
K
E
F
E
E
F
F
S
Q
W
G
T
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.3
30.1
96.6
N.A.
99.4
99.7
N.A.
65.4
31.4
32
80.9
N.A.
52.8
N.A.
28.1
N.A.
Protein Similarity:
100
75.4
44.4
96.6
N.A.
99.7
99.7
N.A.
72.3
45.8
45.5
87
N.A.
64.7
N.A.
42.5
N.A.
P-Site Identity:
100
6.6
26.6
93.3
N.A.
93.3
93.3
N.A.
93.3
13.3
40
0
N.A.
73.3
N.A.
33.3
N.A.
P-Site Similarity:
100
20
33.3
93.3
N.A.
93.3
93.3
N.A.
93.3
26.6
66.6
13.3
N.A.
86.6
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
47
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
16
47
16
8
8
24
0
8
47
0
8
8
8
8
% E
% Phe:
0
0
8
0
8
8
0
8
77
0
0
54
0
0
0
% F
% Gly:
8
0
0
0
8
8
0
8
8
0
8
8
62
0
0
% G
% His:
0
8
0
0
0
0
16
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
8
0
0
8
0
0
0
0
16
0
16
% I
% Lys:
8
0
16
8
0
70
8
0
0
0
16
0
0
54
0
% K
% Leu:
0
8
8
0
16
0
8
8
0
16
0
0
0
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
16
0
0
8
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
0
54
0
0
0
0
% Q
% Arg:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
8
0
8
8
0
0
0
0
% S
% Thr:
47
8
8
8
0
8
0
0
0
8
8
8
0
24
0
% T
% Val:
8
39
0
16
54
0
16
0
8
8
0
0
0
8
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _