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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI1
All Species:
11.82
Human Site:
S255
Identified Species:
21.67
UniProt:
O43347
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43347
NP_002433.1
362
39125
S255
V
E
R
T
P
L
P
S
A
P
V
L
P
E
L
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
V219
M
L
G
Y
P
N
F
V
A
T
Y
G
R
G
Y
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
N215
G
G
F
G
G
N
D
N
F
G
R
G
G
N
F
Dog
Lupus familis
XP_854252
351
38019
F243
A
P
G
Y
T
Y
Q
F
P
E
F
R
V
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61474
362
39101
S255
V
E
R
S
P
L
P
S
A
P
V
L
P
E
L
Rat
Rattus norvegicus
Q8K3P4
362
39115
S255
V
E
R
T
P
L
P
S
A
P
V
L
P
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
P238
P
S
Y
S
Y
Q
F
P
G
F
P
A
A
A
A
Chicken
Gallus gallus
Q5ZI72
301
33425
Y196
V
A
Q
P
K
E
V
Y
R
Q
Q
Q
Q
Q
Q
Frog
Xenopus laevis
Q98SJ2
360
39210
P255
Q
P
A
G
R
G
G
P
P
P
P
P
S
F
A
Zebra Danio
Brachydanio rerio
NP_001013534
330
35800
T225
G
Y
P
G
F
Q
A
T
T
Y
A
G
R
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
N260
Y
P
T
V
D
L
T
N
G
Q
L
T
P
N
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
Y241
Q
R
G
G
P
G
A
Y
G
G
P
G
G
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
T396
K
Q
T
G
M
D
Y
T
Q
M
Y
Q
Q
Q
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.3
30.1
96.6
N.A.
99.4
99.7
N.A.
65.4
31.4
32
80.9
N.A.
52.8
N.A.
28.1
N.A.
Protein Similarity:
100
75.4
44.4
96.6
N.A.
99.7
99.7
N.A.
72.3
45.8
45.5
87
N.A.
64.7
N.A.
42.5
N.A.
P-Site Identity:
100
13.3
0
6.6
N.A.
93.3
100
N.A.
0
6.6
6.6
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
20
6.6
6.6
N.A.
100
100
N.A.
6.6
20
6.6
6.6
N.A.
26.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
16
0
31
0
8
8
8
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
24
0
0
0
8
0
0
0
8
0
0
0
31
0
% E
% Phe:
0
0
8
0
8
0
16
8
8
8
8
0
0
8
8
% F
% Gly:
16
8
24
39
8
16
8
0
24
16
0
31
16
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
31
0
0
0
0
8
24
0
0
24
% L
% Met:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
16
0
16
0
0
0
0
0
16
8
% N
% Pro:
8
24
8
8
39
0
24
16
16
31
24
8
31
0
0
% P
% Gln:
16
8
8
0
0
16
8
0
8
16
8
16
16
16
8
% Q
% Arg:
0
8
24
0
8
0
0
0
8
0
8
8
16
0
8
% R
% Ser:
0
8
0
16
0
0
0
24
0
0
0
0
8
8
0
% S
% Thr:
0
0
16
16
8
0
8
16
8
8
0
8
0
0
0
% T
% Val:
31
0
0
8
0
0
8
8
0
0
24
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
8
16
8
8
8
16
0
8
16
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _