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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI1
All Species:
13.64
Human Site:
S12
Identified Species:
25
UniProt:
O43347
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43347
NP_002433.1
362
39125
S12
A
P
Q
P
G
L
A
S
P
D
S
P
H
D
P
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
Dog
Lupus familis
XP_854252
351
38019
S12
A
P
Q
P
G
L
A
S
P
D
S
P
H
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61474
362
39101
S12
A
P
Q
P
G
L
A
S
P
D
S
P
H
D
P
Rat
Rattus norvegicus
Q8K3P4
362
39115
S12
A
P
Q
P
G
L
A
S
P
D
S
P
H
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
M12
T
S
V
L
T
S
V
M
F
S
S
S
S
K
M
Chicken
Gallus gallus
Q5ZI72
301
33425
Frog
Xenopus laevis
Q98SJ2
360
39210
G16
I
G
K
L
F
V
G
G
L
D
W
S
T
T
Q
Zebra Danio
Brachydanio rerio
NP_001013534
330
35800
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
P21
V
E
L
G
P
C
S
P
S
E
V
P
N
D
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
A15
A
E
N
G
S
G
D
A
S
L
E
P
E
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
K151
Q
T
K
E
E
R
S
K
A
D
L
S
K
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.3
30.1
96.6
N.A.
99.4
99.7
N.A.
65.4
31.4
32
80.9
N.A.
52.8
N.A.
28.1
N.A.
Protein Similarity:
100
75.4
44.4
96.6
N.A.
99.7
99.7
N.A.
72.3
45.8
45.5
87
N.A.
64.7
N.A.
42.5
N.A.
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
6.6
0
6.6
0
N.A.
20
N.A.
13.3
N.A.
P-Site Similarity:
100
0
0
100
N.A.
100
100
N.A.
6.6
0
20
0
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
0
0
0
31
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
47
0
0
0
39
0
% D
% Glu:
0
16
0
8
8
0
0
0
0
8
8
0
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
0
16
31
8
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
16
0
0
0
0
8
0
0
0
0
8
8
0
% K
% Leu:
0
0
8
16
0
31
0
0
8
8
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
31
0
31
8
0
0
8
31
0
0
47
0
0
39
% P
% Gln:
8
0
31
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
8
16
31
16
8
39
24
8
0
8
% S
% Thr:
8
8
0
0
8
0
0
0
0
0
0
0
8
8
0
% T
% Val:
8
0
8
0
0
8
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _