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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF9
All Species:
10.61
Human Site:
T448
Identified Species:
38.89
UniProt:
O43307
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43307
NP_056000.1
516
60982
T448
Q
K
R
Q
A
A
M
T
V
R
K
V
P
K
Q
Chimpanzee
Pan troglodytes
XP_001152034
1339
148093
S1271
Q
K
K
L
A
M
L
S
A
Q
K
A
G
H
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543166
507
59095
N439
M
G
M
E
I
S
E
N
Q
K
K
L
A
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTH8
516
60909
T448
Q
K
R
Q
A
A
M
T
V
R
K
A
S
K
Q
Rat
Rattus norvegicus
Q9QX73
493
58139
L424
L
E
E
K
I
R
W
L
R
A
F
R
E
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515401
453
53736
T385
Q
K
R
Q
A
A
M
T
V
R
K
V
S
K
Q
Chicken
Gallus gallus
XP_420291
518
61066
K432
R
A
F
R
E
E
R
K
M
V
K
E
D
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.7
N.A.
62.5
N.A.
98.4
88.3
N.A.
82.9
92.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
31
N.A.
76.1
N.A.
98.8
90.3
N.A.
86
96.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
N.A.
6.6
N.A.
86.6
0
N.A.
93.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
N.A.
33.3
N.A.
86.6
26.6
N.A.
93.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
58
43
0
0
15
15
0
29
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
0
15
15
15
15
15
15
0
0
0
0
15
15
29
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
15
0
0
0
0
% F
% Gly:
0
15
0
0
0
0
0
0
0
0
0
0
15
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% H
% Ile:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
58
15
15
0
0
0
15
0
15
86
0
0
43
15
% K
% Leu:
15
0
0
15
0
0
15
15
0
0
0
15
0
0
15
% L
% Met:
15
0
15
0
0
15
43
0
15
0
0
0
0
15
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
58
0
0
43
0
0
0
0
15
15
0
0
0
0
43
% Q
% Arg:
15
0
43
15
0
15
15
0
15
43
0
15
0
0
15
% R
% Ser:
0
0
0
0
0
15
0
15
0
0
0
0
29
0
0
% S
% Thr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
43
15
0
29
0
0
0
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _