KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC14L5
All Species:
26.97
Human Site:
Y464
Identified Species:
53.94
UniProt:
O43304
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43304
NP_055507.1
696
78942
Y464
G
P
G
G
L
V
D
Y
L
D
R
E
V
I
P
Chimpanzee
Pan troglodytes
XP_001155788
703
80307
Y465
G
P
G
G
L
L
D
Y
I
D
K
E
I
I
P
Rhesus Macaque
Macaca mulatta
XP_001098962
775
87125
Y543
G
P
G
G
L
V
D
Y
L
D
R
E
V
I
P
Dog
Lupus familis
XP_547140
695
78724
Y464
G
P
G
G
L
V
D
Y
L
D
R
D
V
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0F9
403
46035
F175
V
E
V
Y
Q
Q
F
F
A
I
L
E
A
N
Y
Rat
Rattus norvegicus
Q99MS0
403
46148
L175
V
E
A
Y
G
E
F
L
T
M
F
E
E
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414710
694
78680
Y457
G
P
G
G
L
V
D
Y
V
D
K
E
V
I
P
Frog
Xenopus laevis
NP_001087870
715
81309
Y477
G
P
G
G
L
I
D
Y
I
D
K
E
V
I
P
Zebra Danio
Brachydanio rerio
NP_957392
697
79632
Y459
G
P
G
G
L
V
D
Y
I
N
K
D
C
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMD6
659
75661
K426
I
D
E
H
T
R
S
K
F
L
F
Y
G
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03606
719
81064
H477
L
K
E
E
L
R
K
H
I
E
E
K
F
I
P
Sea Urchin
Strong. purpuratus
XP_783768
1178
131796
H942
E
S
G
G
L
T
D
H
I
T
P
Q
Y
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
87.3
91
N.A.
21.8
21.9
N.A.
N.A.
75.1
66.1
63.7
N.A.
41.5
N.A.
45
32
Protein Similarity:
100
84
88.1
94.9
N.A.
35.6
37.6
N.A.
N.A.
85.1
83
80.3
N.A.
61.2
N.A.
64.8
43.6
P-Site Identity:
100
73.3
100
93.3
N.A.
6.6
6.6
N.A.
N.A.
86.6
80
66.6
N.A.
0
N.A.
20
33.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
6.6
N.A.
N.A.
100
100
93.3
N.A.
0
N.A.
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
9
0
0
0
0
67
0
0
50
0
17
0
0
9
% D
% Glu:
9
17
17
9
0
9
0
0
0
9
9
59
9
0
0
% E
% Phe:
0
0
0
0
0
0
17
9
9
0
17
0
9
0
0
% F
% Gly:
59
0
67
67
9
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
9
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
9
0
0
42
9
0
0
9
67
0
% I
% Lys:
0
9
0
0
0
0
9
9
0
0
34
9
0
0
0
% K
% Leu:
9
0
0
0
75
9
0
9
25
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
17
0
% N
% Pro:
0
59
0
0
0
0
0
0
0
0
9
0
0
9
75
% P
% Gln:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
17
0
0
0
0
25
0
0
0
0
% R
% Ser:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
9
0
0
9
9
0
0
0
0
0
% T
% Val:
17
0
9
0
0
42
0
0
9
0
0
0
42
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
59
0
0
0
9
9
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _