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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC14L5
All Species:
20.3
Human Site:
S677
Identified Species:
40.61
UniProt:
O43304
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43304
NP_055507.1
696
78942
S677
T
S
G
F
S
Q
L
S
A
A
T
S
S
S
S
Chimpanzee
Pan troglodytes
XP_001155788
703
80307
S678
S
M
T
S
L
E
S
S
H
S
G
F
S
Q
L
Rhesus Macaque
Macaca mulatta
XP_001098962
775
87125
S756
T
S
G
F
S
Q
L
S
A
A
T
S
S
S
S
Dog
Lupus familis
XP_547140
695
78724
S677
T
S
G
F
S
Q
L
S
A
T
T
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0F9
403
46035
L385
G
Y
T
A
E
V
L
L
P
D
K
A
C
E
E
Rat
Rattus norvegicus
Q99MS0
403
46148
L385
S
F
T
V
E
V
L
L
P
D
K
A
A
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414710
694
78680
S671
S
S
L
E
S
C
N
S
G
F
S
Q
L
S
G
Frog
Xenopus laevis
NP_001087870
715
81309
S690
S
M
T
S
L
E
S
S
H
S
G
F
S
Q
L
Zebra Danio
Brachydanio rerio
NP_957392
697
79632
S672
S
M
S
S
L
E
S
S
H
S
G
F
S
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMD6
659
75661
S641
N
Y
K
G
S
M
T
S
L
Q
S
A
F
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03606
719
81064
A692
E
N
F
R
G
S
V
A
S
L
E
S
C
R
S
Sea Urchin
Strong. purpuratus
XP_783768
1178
131796
S1156
H
S
G
F
S
S
L
S
I
S
T
T
S
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
87.3
91
N.A.
21.8
21.9
N.A.
N.A.
75.1
66.1
63.7
N.A.
41.5
N.A.
45
32
Protein Similarity:
100
84
88.1
94.9
N.A.
35.6
37.6
N.A.
N.A.
85.1
83
80.3
N.A.
61.2
N.A.
64.8
43.6
P-Site Identity:
100
13.3
100
93.3
N.A.
6.6
6.6
N.A.
N.A.
26.6
13.3
13.3
N.A.
26.6
N.A.
13.3
60
P-Site Similarity:
100
33.3
100
93.3
N.A.
13.3
26.6
N.A.
N.A.
40
33.3
33.3
N.A.
40
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
25
17
0
25
9
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
17
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
9
0
0
9
17
25
0
0
0
0
9
0
0
17
17
% E
% Phe:
0
9
9
34
0
0
0
0
0
9
0
25
9
0
0
% F
% Gly:
9
0
34
9
9
0
0
0
9
0
25
0
0
0
9
% G
% His:
9
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
17
0
0
0
0
% K
% Leu:
0
0
9
0
25
0
50
17
9
9
0
0
9
9
25
% L
% Met:
0
25
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
25
0
0
0
9
0
9
0
17
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
9
% R
% Ser:
42
42
9
25
50
17
25
75
9
34
17
34
59
50
42
% S
% Thr:
25
0
34
0
0
0
9
0
0
9
34
9
0
0
0
% T
% Val:
0
0
0
9
0
17
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _