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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC14L5
All Species:
9.09
Human Site:
S172
Identified Species:
18.18
UniProt:
O43304
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43304
NP_055507.1
696
78942
S172
H
Y
L
N
E
L
I
S
Q
G
T
S
H
I
P
Chimpanzee
Pan troglodytes
XP_001155788
703
80307
E172
Y
Y
L
R
Q
L
E
E
E
G
I
T
F
V
P
Rhesus Macaque
Macaca mulatta
XP_001098962
775
87125
S251
H
Y
L
N
E
L
I
S
Q
G
T
S
H
I
P
Dog
Lupus familis
XP_547140
695
78724
S172
H
Y
L
N
E
L
I
S
Q
G
T
S
H
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0F9
403
46035
Rat
Rattus norvegicus
Q99MS0
403
46148
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414710
694
78680
P168
F
I
P
R
W
T
P
P
V
A
H
G
Q
K
A
Frog
Xenopus laevis
NP_001087870
715
81309
Q172
Y
Y
L
N
Q
L
E
Q
E
G
I
T
S
M
P
Zebra Danio
Brachydanio rerio
NP_957392
697
79632
E171
E
F
H
L
K
Q
L
E
E
E
G
I
T
H
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VMD6
659
75661
E172
F
F
I
G
Q
L
R
E
E
G
I
T
H
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03606
719
81064
K172
F
F
I
E
E
L
L
K
K
T
T
H
I
E
R
Sea Urchin
Strong. purpuratus
XP_783768
1178
131796
A649
Y
Y
I
Q
E
I
L
A
E
G
E
T
D
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
87.3
91
N.A.
21.8
21.9
N.A.
N.A.
75.1
66.1
63.7
N.A.
41.5
N.A.
45
32
Protein Similarity:
100
84
88.1
94.9
N.A.
35.6
37.6
N.A.
N.A.
85.1
83
80.3
N.A.
61.2
N.A.
64.8
43.6
P-Site Identity:
100
33.3
100
100
N.A.
0
0
N.A.
N.A.
0
40
0
N.A.
20
N.A.
20
26.6
P-Site Similarity:
100
66.6
100
100
N.A.
0
0
N.A.
N.A.
0
73.3
26.6
N.A.
60
N.A.
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
9
0
0
9
42
0
17
25
42
9
9
0
0
9
9
% E
% Phe:
25
25
0
0
0
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
59
9
9
0
0
0
% G
% His:
25
0
9
0
0
0
0
0
0
0
9
9
34
9
0
% H
% Ile:
0
9
25
0
0
9
25
0
0
0
25
9
9
25
0
% I
% Lys:
0
0
0
0
9
0
0
9
9
0
0
0
0
9
0
% K
% Leu:
0
0
42
9
0
59
25
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% M
% Asn:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
9
0
0
0
0
0
0
50
% P
% Gln:
0
0
0
9
25
9
0
9
25
0
0
0
9
0
0
% Q
% Arg:
0
0
0
17
0
0
9
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
25
0
0
0
25
9
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
9
34
34
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _