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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRGAP3 All Species: 26.97
Human Site: S405 Identified Species: 74.17
UniProt: O43295 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43295 NP_001028289.1 1099 124504 S405 V S D A F Q H S R S T E S V K
Chimpanzee Pan troglodytes XP_509190 1085 124290 S405 V S E C F Q H S R S T E S V K
Rhesus Macaque Macaca mulatta XP_001097218 1099 124453 S405 V S D A F Q H S R S T E S V K
Dog Lupus familis XP_852764 1099 124453 S405 V S D A F Q H S R S T E S V K
Cat Felis silvestris
Mouse Mus musculus Q812A2 1099 124401 S405 V S D A F Q H S R S T E S I K
Rat Rattus norvegicus XP_575637 1099 124429 S405 V S D A F Q H S R S T E S I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507094 844 96985 E180 L K E A E K Q E E K Q Y N K S
Chicken Gallus gallus NP_001025775 853 98054 E189 K E A E K Q E E K Q F N K S G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690072 1094 123926 S400 V S D A F Q H S R S T E S I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.4 99 99.3 N.A. 98.5 98.6 N.A. 61 74 N.A. 87.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 81.1 99.2 99.7 N.A. 99.6 99.7 N.A. 67 76.2 N.A. 93.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 100 100 N.A. 93.3 93.3 N.A. 6.6 6.6 N.A. 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 33.3 13.3 N.A. 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 78 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 12 23 12 12 0 12 23 12 0 0 78 0 0 0 % E
% Phe: 0 0 0 0 78 0 0 0 0 0 12 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % I
% Lys: 12 12 0 0 12 12 0 0 12 12 0 0 12 12 78 % K
% Leu: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 12 12 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 89 12 0 0 12 12 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 % R
% Ser: 0 78 0 0 0 0 0 78 0 78 0 0 78 12 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 78 0 0 0 0 % T
% Val: 78 0 0 0 0 0 0 0 0 0 0 0 0 45 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _