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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFS
All Species:
16.06
Human Site:
Y217
Identified Species:
39.26
UniProt:
O43281
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43281
NP_005855.1
561
58815
Y217
R
E
P
G
P
P
I
Y
A
A
P
S
N
L
K
Chimpanzee
Pan troglodytes
XP_509854
560
58758
Y216
R
E
P
G
P
P
I
Y
A
A
P
S
N
L
K
Rhesus Macaque
Macaca mulatta
XP_001107716
561
59118
Y217
R
E
P
G
P
P
I
Y
A
A
P
S
N
L
K
Dog
Lupus familis
XP_537374
621
65274
Y277
R
E
P
E
P
P
L
Y
A
A
P
S
N
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64355
560
58952
L216
G
R
E
P
G
P
P
L
Y
A
A
P
S
N
L
Rat
Rattus norvegicus
Q63767
968
104244
V556
R
E
P
L
E
L
E
V
A
V
E
T
L
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514732
886
98573
H353
L
Y
D
I
P
P
S
H
Q
S
P
Q
A
G
Q
Chicken
Gallus gallus
XP_418946
857
95485
H328
V
Y
D
I
P
V
N
H
Q
N
H
F
L
G
Q
Frog
Xenopus laevis
NP_001088375
646
70440
Y215
D
E
E
D
E
G
V
Y
S
M
P
S
N
L
K
Zebra Danio
Brachydanio rerio
NP_001128605
919
102207
H408
R
K
G
G
P
Q
D
H
H
P
T
D
V
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.7
79.3
N.A.
80.7
26.8
N.A.
27.4
26.2
30.3
27.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
96.7
82.1
N.A.
85.1
35.7
N.A.
38.1
38.6
42.8
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
13.3
26.6
N.A.
20
6.6
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
20
40
N.A.
40
20
60
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
50
50
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
20
10
0
0
10
0
0
0
0
10
0
0
10
% D
% Glu:
0
60
20
10
20
0
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
10
40
10
10
0
0
0
0
0
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
30
10
0
10
0
0
0
0
% H
% Ile:
0
0
0
20
0
0
30
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
50
% K
% Leu:
10
0
0
10
0
10
10
10
0
0
0
0
20
50
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
50
10
0
% N
% Pro:
0
0
50
10
70
60
10
0
0
10
60
10
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
20
0
0
10
0
0
20
% Q
% Arg:
60
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
10
0
10
10
0
50
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
10
0
0
0
0
10
10
10
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
0
50
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _