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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
29.09
Human Site:
Y46
Identified Species:
49.23
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
Y46
C
N
M
I
S
K
K
Y
S
E
F
L
P
S
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
Y46
C
N
M
I
S
K
K
Y
S
E
F
L
P
S
M
Dog
Lupus familis
XP_536569
779
88803
Y46
C
T
M
I
S
K
K
Y
S
E
F
L
P
S
M
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
Y46
C
N
M
I
S
K
K
Y
S
E
F
L
P
T
M
Rat
Rattus norvegicus
Q4V8C2
777
87948
Y46
C
N
M
I
S
K
K
Y
S
E
F
L
P
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
Chicken
Gallus gallus
NP_989914
753
85635
V46
V
D
G
L
S
R
S
V
D
L
L
R
A
G
V
Frog
Xenopus laevis
NP_001131044
776
88019
Y46
C
D
M
I
N
K
K
Y
D
E
F
L
P
S
M
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
Y46
T
D
M
I
N
K
K
Y
I
E
F
I
P
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
R38
A
I
L
K
V
L
T
R
V
N
R
F
Q
M
R
Honey Bee
Apis mellifera
XP_001121600
710
82808
I27
L
H
E
K
I
S
E
I
Q
K
E
I
T
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
Y46
S
H
A
L
R
Q
R
Y
V
D
F
I
P
S
Q
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
K46
E
S
H
S
L
Q
I
K
S
K
V
K
S
Y
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
I48
L
E
S
H
S
L
R
I
K
S
K
V
Q
S
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
0
6.6
80
66.6
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
0
33.3
93.3
86.6
N.A.
6.6
33.3
N.A.
66.6
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
0
0
0
0
0
0
15
8
0
0
0
0
0
% D
% Glu:
8
8
8
0
0
0
8
0
0
50
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
58
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
15
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
50
8
0
8
15
8
0
0
22
0
0
8
% I
% Lys:
0
0
0
15
0
50
50
8
8
15
8
8
0
8
0
% K
% Leu:
15
0
8
15
8
15
0
0
0
8
8
43
0
0
8
% L
% Met:
0
0
50
0
0
0
0
0
0
0
0
0
0
8
50
% M
% Asn:
0
29
0
0
15
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% P
% Gln:
0
0
0
0
0
15
0
0
8
0
0
0
15
0
8
% Q
% Arg:
0
0
0
0
8
8
15
8
0
0
8
8
0
0
8
% R
% Ser:
8
8
8
8
50
8
8
0
43
8
0
0
8
50
0
% S
% Thr:
8
8
0
0
0
0
8
0
0
0
0
0
8
15
0
% T
% Val:
8
0
0
0
8
0
0
8
15
0
8
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _