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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
22.12
Human Site:
T61
Identified Species:
37.44
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
T61
Q
S
A
Q
G
L
I
T
Q
V
D
K
L
S
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
T61
Q
S
A
Q
G
L
I
T
Q
V
D
K
L
S
E
Dog
Lupus familis
XP_536569
779
88803
T61
Q
S
A
Q
D
L
V
T
Q
V
D
K
L
S
E
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
T61
Q
S
A
Q
A
L
V
T
Q
V
D
T
L
S
N
Rat
Rattus norvegicus
Q4V8C2
777
87948
T61
Q
S
A
Q
A
L
V
T
Q
V
D
T
L
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
Chicken
Gallus gallus
NP_989914
753
85635
L61
E
N
E
V
Q
R
D
L
T
V
A
V
A
E
F
Frog
Xenopus laevis
NP_001131044
776
88019
T61
Q
S
A
E
D
L
V
T
Q
V
H
G
L
V
S
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
D61
E
G
A
E
E
L
L
D
Q
V
E
S
V
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
N53
V
R
K
H
I
E
D
N
Y
T
E
F
L
P
N
Honey Bee
Apis mellifera
XP_001121600
710
82808
M42
K
Y
D
V
K
D
F
M
D
D
N
Y
V
E
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
T61
D
K
I
E
K
M
H
T
R
V
R
S
L
D
T
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
S61
L
A
H
H
S
D
F
S
S
L
F
S
L
C
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
F63
L
V
A
H
H
S
D
F
S
E
L
F
S
L
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
86.6
N.A.
73.3
73.3
N.A.
0
6.6
53.3
33.3
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
80
N.A.
0
20
66.6
73.3
N.A.
13.3
20
N.A.
40
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
58
0
15
0
0
0
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
8
0
15
15
22
8
8
8
36
0
0
8
0
% D
% Glu:
15
0
8
22
8
8
0
0
0
8
15
0
0
15
22
% E
% Phe:
0
0
0
0
0
0
15
8
0
0
8
15
0
0
15
% F
% Gly:
0
8
0
0
15
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
8
22
8
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
8
0
15
0
0
0
0
0
0
22
0
0
8
% K
% Leu:
15
0
0
0
0
50
8
8
0
8
8
0
65
8
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
29
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
43
0
0
36
8
0
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
8
0
8
0
0
0
0
% R
% Ser:
0
43
0
0
8
8
0
8
15
0
0
22
8
43
8
% S
% Thr:
0
0
0
0
0
0
0
50
8
8
0
15
0
0
8
% T
% Val:
8
8
0
15
0
0
29
0
0
65
0
8
15
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _