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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
17.58
Human Site:
T466
Identified Species:
29.74
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
T466
M
N
L
E
P
E
N
T
L
D
Q
H
S
F
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
T465
V
N
L
E
P
E
N
T
L
D
Q
H
S
F
S
Dog
Lupus familis
XP_536569
779
88803
T466
V
N
L
E
P
E
N
T
L
D
Q
H
S
F
S
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
S466
G
N
L
E
P
E
T
S
L
D
P
Q
S
F
S
Rat
Rattus norvegicus
Q4V8C2
777
87948
S464
G
N
L
E
P
E
T
S
L
D
P
R
S
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
S360
T
L
L
E
A
T
T
S
T
E
Q
C
A
V
Q
Chicken
Gallus gallus
NP_989914
753
85635
R452
T
F
S
L
P
T
C
R
I
S
A
S
V
E
K
Frog
Xenopus laevis
NP_001131044
776
88019
K463
P
G
L
E
N
N
V
K
L
S
Q
H
T
F
A
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
Q459
Q
S
L
E
N
E
K
Q
L
S
P
N
T
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
R442
N
D
P
F
L
F
P
R
C
M
I
S
K
S
A
Honey Bee
Apis mellifera
XP_001121600
710
82808
A431
A
K
E
I
L
D
L
A
R
N
I
L
D
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
D457
E
S
V
Q
K
L
L
D
M
C
K
Q
T
L
Y
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
A457
R
C
L
V
S
K
A
A
T
Q
L
M
D
L
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
C462
H
K
T
L
E
D
V
C
V
S
S
A
R
V
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
66.6
66.6
N.A.
20
6.6
40
26.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
100
100
N.A.
73.3
73.3
N.A.
40
13.3
53.3
46.6
N.A.
13.3
20
N.A.
40
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
15
0
0
8
8
8
0
29
% A
% Cys:
0
8
0
0
0
0
8
8
8
8
0
8
0
0
8
% C
% Asp:
0
8
0
0
0
15
0
8
0
36
0
0
15
0
0
% D
% Glu:
8
0
8
58
8
43
0
0
0
8
0
0
0
15
0
% E
% Phe:
0
8
0
8
0
8
0
0
0
0
0
0
0
43
0
% F
% Gly:
15
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
29
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
0
15
0
0
0
0
% I
% Lys:
0
15
0
0
8
8
8
8
0
0
8
0
8
0
8
% K
% Leu:
0
8
65
15
15
8
15
0
50
0
8
8
0
22
0
% L
% Met:
8
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% M
% Asn:
8
36
0
0
15
8
22
0
0
8
0
8
0
0
0
% N
% Pro:
8
0
8
0
43
0
8
0
0
0
22
0
0
0
0
% P
% Gln:
8
0
0
8
0
0
0
8
0
8
36
15
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
15
8
0
0
8
8
0
0
% R
% Ser:
0
15
8
0
8
0
0
22
0
29
8
15
36
8
36
% S
% Thr:
15
0
8
0
0
15
22
22
15
0
0
0
22
0
0
% T
% Val:
15
0
8
8
0
0
15
0
8
0
0
0
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _