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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
13.03
Human Site:
T438
Identified Species:
22.05
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
T438
I
N
V
P
E
L
P
T
P
D
E
D
N
K
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
T437
I
N
V
P
E
L
P
T
P
D
E
D
N
K
L
Dog
Lupus familis
XP_536569
779
88803
C438
I
N
V
P
A
L
P
C
P
E
K
D
E
K
P
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
S438
E
A
L
P
D
L
P
S
P
D
A
D
H
K
L
Rat
Rattus norvegicus
Q4V8C2
777
87948
P436
E
E
T
L
P
D
L
P
S
P
D
A
D
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
F332
S
K
L
G
E
R
S
F
S
L
P
E
C
R
I
Chicken
Gallus gallus
NP_989914
753
85635
K424
G
D
H
V
K
M
Q
K
T
S
K
L
P
N
E
Frog
Xenopus laevis
NP_001131044
776
88019
L435
C
K
I
T
V
P
V
L
P
K
S
E
G
S
E
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
S431
L
S
I
P
K
L
L
S
P
S
G
G
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
I414
L
E
T
A
R
E
I
I
Q
R
D
L
Q
D
M
Honey Bee
Apis mellifera
XP_001121600
710
82808
K403
I
D
N
Y
N
E
I
K
V
N
K
K
I
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
S429
T
S
A
D
E
E
G
S
A
E
E
K
N
P
L
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
K429
T
R
K
G
H
P
M
K
N
S
G
T
A
V
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
L434
N
A
K
H
I
V
C
L
L
F
S
S
E
R
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
60
N.A.
53.3
0
N.A.
6.6
0
6.6
26.6
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
N.A.
100
73.3
N.A.
80
13.3
N.A.
33.3
26.6
20
60
N.A.
20
26.6
N.A.
46.6
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
8
8
0
0
0
8
0
8
8
8
0
0
% A
% Cys:
8
0
0
0
0
0
8
8
0
0
0
0
8
0
8
% C
% Asp:
0
15
0
8
8
8
0
0
0
22
15
29
8
8
8
% D
% Glu:
15
15
0
0
29
22
0
0
0
15
22
15
22
0
22
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
15
0
0
8
0
0
0
15
8
8
0
0
% G
% His:
0
0
8
8
8
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
29
0
15
0
8
0
15
8
0
0
0
0
8
0
8
% I
% Lys:
0
15
15
0
15
0
0
22
0
8
22
15
0
36
0
% K
% Leu:
15
0
15
8
0
36
15
15
8
8
0
15
0
0
29
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
8
% M
% Asn:
8
22
8
0
8
0
0
0
8
8
0
0
22
15
8
% N
% Pro:
0
0
0
36
8
15
29
8
43
8
8
0
8
8
8
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% Q
% Arg:
0
8
0
0
8
8
0
0
0
8
0
0
0
15
8
% R
% Ser:
8
15
0
0
0
0
8
22
15
22
15
8
0
8
0
% S
% Thr:
15
0
15
8
0
0
0
15
8
0
0
8
0
0
0
% T
% Val:
0
0
22
8
8
8
8
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _