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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
18.48
Human Site:
T422
Identified Species:
31.28
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
T422
M
T
S
E
I
H
N
T
V
K
I
I
P
D
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
T421
M
T
S
E
I
H
N
T
V
K
I
I
P
D
S
Dog
Lupus familis
XP_536569
779
88803
T422
M
T
S
E
I
H
N
T
V
K
I
T
P
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
T422
M
T
S
E
I
H
N
T
V
K
I
G
P
D
C
Rat
Rattus norvegicus
Q4V8C2
777
87948
N420
L
M
T
S
E
I
H
N
T
V
K
I
G
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
D316
K
E
A
R
A
G
P
D
D
G
M
N
L
E
P
Chicken
Gallus gallus
NP_989914
753
85635
L408
T
P
D
S
S
V
A
L
P
K
L
P
D
P
G
Frog
Xenopus laevis
NP_001131044
776
88019
H419
N
L
M
T
S
E
I
H
N
T
V
K
I
T
P
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
T415
M
T
S
E
M
H
N
T
V
K
I
T
P
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
Y398
V
E
K
Y
E
T
Y
Y
R
N
R
M
Y
R
R
Honey Bee
Apis mellifera
XP_001121600
710
82808
Q387
D
S
I
I
Y
E
P
Q
E
P
L
E
F
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
N413
L
M
Q
Q
D
L
H
N
T
V
E
V
G
G
I
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
C413
A
R
N
L
L
L
Q
C
D
F
T
I
P
Q
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
T418
L
L
L
Q
C
N
F
T
I
P
Q
D
I
A
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
6.6
N.A.
0
6.6
0
73.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
100
86.6
N.A.
86.6
26.6
N.A.
20
13.3
6.6
86.6
N.A.
13.3
13.3
N.A.
26.6
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
8
0
8
0
8
0
0
8
15
0
0
8
8
29
8
% D
% Glu:
0
15
0
36
15
15
0
0
8
0
8
8
0
15
15
% E
% Phe:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
0
8
15
8
8
% G
% His:
0
0
0
0
0
36
15
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
29
8
8
0
8
0
36
29
15
0
8
% I
% Lys:
8
0
8
0
0
0
0
0
0
43
8
8
0
0
0
% K
% Leu:
22
15
8
8
8
15
0
8
0
0
15
0
8
8
0
% L
% Met:
36
15
8
0
8
0
0
0
0
0
8
8
0
0
8
% M
% Asn:
8
0
8
0
0
8
36
15
8
8
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
15
0
8
15
0
8
43
15
15
% P
% Gln:
0
0
8
15
0
0
8
8
0
0
8
0
0
8
0
% Q
% Arg:
0
8
0
8
0
0
0
0
8
0
8
0
0
8
8
% R
% Ser:
0
8
36
15
15
0
0
0
0
0
0
0
0
0
15
% S
% Thr:
8
36
8
8
0
8
0
43
15
8
8
15
0
8
0
% T
% Val:
8
0
0
0
0
8
0
0
36
15
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
8
8
0
0
0
0
8
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _