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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
16.67
Human Site:
T282
Identified Species:
28.21
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
T282
I
R
F
E
S
I
M
T
N
L
E
Y
P
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
N282
R
F
E
S
I
M
T
N
L
E
Y
P
S
P
S
Dog
Lupus familis
XP_536569
779
88803
T282
I
R
F
E
S
V
M
T
D
L
E
H
P
S
P
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
T282
I
C
F
E
S
L
T
T
D
L
E
H
P
S
P
Rat
Rattus norvegicus
Q4V8C2
777
87948
T281
I
C
F
Q
S
L
A
T
D
S
E
H
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
E188
T
S
K
M
V
L
A
E
I
L
G
D
M
I
W
Chicken
Gallus gallus
NP_989914
753
85635
H279
K
F
I
L
E
V
L
H
K
Y
L
L
N
V
P
Frog
Xenopus laevis
NP_001131044
776
88019
T281
L
R
F
E
S
I
E
T
Q
L
E
H
P
P
P
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
Q280
Q
G
A
V
L
S
L
Q
C
L
E
T
K
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
E270
P
V
M
A
D
Y
S
E
E
A
D
G
G
T
Y
Honey Bee
Apis mellifera
XP_001121600
710
82808
I259
E
K
I
F
T
V
E
I
L
K
K
K
K
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
S280
E
Q
L
S
S
I
P
S
P
N
A
V
F
D
S
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
K280
E
M
T
E
A
I
L
K
I
L
S
T
S
N
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
R282
E
V
T
E
A
T
L
R
L
E
Q
S
S
D
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
0
80
N.A.
66.6
46.6
N.A.
6.6
6.6
66.6
13.3
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
6.6
100
N.A.
86.6
73.3
N.A.
13.3
20
80
26.6
N.A.
13.3
33.3
N.A.
26.6
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
15
0
15
0
0
8
8
0
0
8
0
% A
% Cys:
0
15
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
22
0
8
8
0
15
0
% D
% Glu:
29
0
8
43
8
0
15
15
8
15
43
0
0
0
8
% E
% Phe:
0
15
36
8
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
8
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
29
0
0
8
% H
% Ile:
29
0
15
0
8
29
0
8
15
0
0
0
0
8
0
% I
% Lys:
8
8
8
0
0
0
0
8
8
8
8
8
15
0
0
% K
% Leu:
8
0
8
8
8
22
29
0
22
50
8
8
0
8
0
% L
% Met:
0
8
8
8
0
8
15
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
8
0
0
8
8
0
% N
% Pro:
8
0
0
0
0
0
8
0
8
0
0
8
36
22
58
% P
% Gln:
8
8
0
8
0
0
0
8
8
0
8
0
0
0
0
% Q
% Arg:
8
22
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
15
43
8
8
8
0
8
8
8
22
22
15
% S
% Thr:
8
0
15
0
8
8
15
36
0
0
0
15
0
8
0
% T
% Val:
0
15
0
8
8
22
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
8
0
0
0
8
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _