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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
30.91
Human Site:
T167
Identified Species:
52.31
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
T167
K
S
L
S
M
E
L
T
I
Q
K
Q
N
I
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
T167
K
S
L
S
M
E
L
T
I
Q
K
Q
N
I
L
Dog
Lupus familis
XP_536569
779
88803
T167
K
S
L
S
M
E
L
T
I
Q
K
Q
N
I
L
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
T167
K
S
L
S
M
E
L
T
V
Q
K
Q
N
I
L
Rat
Rattus norvegicus
Q4V8C2
777
87948
T167
K
S
L
S
M
E
L
T
V
Q
K
Q
N
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
E75
L
R
T
E
P
P
K
E
E
E
E
T
P
A
P
Chicken
Gallus gallus
NP_989914
753
85635
P166
K
L
A
V
W
K
L
P
P
S
K
E
T
I
G
Frog
Xenopus laevis
NP_001131044
776
88019
T167
K
S
L
G
I
E
L
T
V
Q
K
Q
N
L
L
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
T167
R
A
L
S
S
E
I
T
I
Q
R
E
N
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
D157
R
A
F
I
Y
G
D
D
S
V
D
G
D
A
Q
Honey Bee
Apis mellifera
XP_001121600
710
82808
Y146
C
H
M
Q
T
I
L
Y
N
S
Q
T
D
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
T167
Q
S
L
K
S
E
E
T
V
V
R
E
T
L
F
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
P167
G
D
E
E
E
R
E
P
V
V
Y
G
L
L
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
D167
L
R
I
G
E
E
E
D
G
E
P
V
A
Y
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
0
26.6
73.3
46.6
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
40
93.3
93.3
N.A.
20
33.3
N.A.
60
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
0
0
0
0
0
0
0
0
0
8
15
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
15
0
0
8
0
15
0
0
% D
% Glu:
0
0
8
15
15
65
22
8
8
15
8
22
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
15
0
8
0
0
8
0
0
15
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
8
8
8
0
29
0
0
0
0
43
8
% I
% Lys:
50
0
0
8
0
8
8
0
0
0
50
0
0
0
0
% K
% Leu:
15
8
58
0
0
0
58
0
0
0
0
0
8
36
43
% L
% Met:
0
0
8
0
36
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
50
0
0
% N
% Pro:
0
0
0
0
8
8
0
15
8
0
8
0
8
0
8
% P
% Gln:
8
0
0
8
0
0
0
0
0
50
8
43
0
0
8
% Q
% Arg:
15
15
0
0
0
8
0
0
0
0
15
0
0
0
15
% R
% Ser:
0
50
0
43
15
0
0
0
8
15
0
0
0
0
0
% S
% Thr:
0
0
8
0
8
0
0
58
0
0
0
15
15
0
0
% T
% Val:
0
0
0
8
0
0
0
0
36
22
0
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _