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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
19.39
Human Site:
S701
Identified Species:
32.82
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
S701
P
Q
V
F
A
P
L
S
E
E
S
K
N
K
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
S700
P
Q
V
F
A
P
L
S
E
E
S
K
N
K
K
Dog
Lupus familis
XP_536569
779
88803
S701
P
H
V
F
A
P
L
S
E
E
S
K
N
T
K
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
S701
P
Q
V
F
A
P
L
S
D
E
N
K
N
K
K
Rat
Rattus norvegicus
Q4V8C2
777
87948
S699
P
Q
V
F
A
P
L
S
D
E
N
K
N
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
E572
A
N
R
K
Y
R
E
E
V
P
V
Y
V
P
K
Chicken
Gallus gallus
NP_989914
753
85635
P675
P
Q
V
F
T
P
L
P
E
E
D
K
N
K
K
Frog
Xenopus laevis
NP_001131044
776
88019
P698
P
L
L
F
T
P
M
P
E
E
T
K
N
K
K
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
P692
P
L
V
F
N
P
L
P
D
E
N
K
N
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
N654
P
T
L
F
R
E
P
N
E
V
V
Q
V
L
S
Honey Bee
Apis mellifera
XP_001121600
710
82808
K643
Q
I
F
P
D
H
Q
K
I
Y
Q
Y
V
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
E669
P
D
I
L
K
P
S
E
S
E
E
P
V
I
M
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
S674
S
S
L
M
E
S
L
S
T
V
I
Q
K
E
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
D674
D
E
T
S
R
P
L
D
D
I
I
P
S
L
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
6.6
80
60
60
N.A.
20
13.3
N.A.
20
P-Site Similarity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
6.6
80
80
80
N.A.
40
13.3
N.A.
26.6
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
36
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
0
0
8
29
0
8
0
0
0
0
% D
% Glu:
0
8
0
0
8
8
8
15
43
65
8
0
0
15
0
% E
% Phe:
0
0
8
65
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
8
8
15
0
0
8
0
% I
% Lys:
0
0
0
8
8
0
0
8
0
0
0
58
8
50
72
% K
% Leu:
0
15
22
8
0
0
65
0
0
0
0
0
0
15
0
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
8
0
0
8
0
0
22
0
58
0
0
% N
% Pro:
72
0
0
8
0
72
8
22
0
8
0
15
0
8
0
% P
% Gln:
8
36
0
0
0
0
8
0
0
0
8
15
0
0
0
% Q
% Arg:
0
0
8
0
15
8
0
0
0
0
0
0
0
0
15
% R
% Ser:
8
8
0
8
0
8
8
43
8
0
22
0
8
0
8
% S
% Thr:
0
8
8
0
15
0
0
0
8
0
8
0
0
8
0
% T
% Val:
0
0
50
0
0
0
0
0
8
15
15
0
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
8
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _