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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
13.03
Human Site:
S662
Identified Species:
22.05
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
S662
T
L
L
N
T
A
I
S
E
V
I
G
K
I
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
S661
T
L
L
N
T
A
I
S
E
I
I
G
K
I
T
Dog
Lupus familis
XP_536569
779
88803
S662
T
L
L
N
T
A
I
S
E
I
I
G
R
I
T
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
A662
T
L
L
N
T
A
I
A
E
M
M
S
R
I
T
Rat
Rattus norvegicus
Q4V8C2
777
87948
A660
T
L
L
N
T
V
I
A
E
M
I
G
R
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
D533
G
R
I
T
A
L
E
D
I
S
T
E
D
G
D
Chicken
Gallus gallus
NP_989914
753
85635
S636
T
L
L
N
T
A
L
S
E
I
V
T
R
I
A
Frog
Xenopus laevis
NP_001131044
776
88019
V659
T
L
L
N
T
A
I
V
E
M
I
S
K
I
T
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
L653
T
L
L
N
T
A
I
L
E
L
I
N
K
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
A615
E
L
I
N
T
F
V
A
E
L
I
R
R
V
F
Honey Bee
Apis mellifera
XP_001121600
710
82808
D604
I
M
N
S
M
I
E
D
L
I
I
R
V
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
M630
T
L
V
N
T
V
L
M
H
V
V
E
Q
I
T
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
A635
M
V
L
E
S
V
F
A
R
V
T
K
D
I
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
D635
A
R
D
I
L
L
L
D
D
M
A
A
D
E
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
66.6
73.3
N.A.
0
60
80
73.3
N.A.
33.3
6.6
N.A.
46.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
6.6
86.6
86.6
80
N.A.
73.3
40
N.A.
73.3
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
50
0
29
0
0
8
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
22
8
0
0
0
22
0
8
% D
% Glu:
8
0
0
8
0
0
15
0
65
0
0
15
0
8
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
29
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
15
8
0
8
50
0
8
29
58
0
0
72
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
29
0
0
% K
% Leu:
0
72
65
0
8
15
22
8
8
15
0
0
0
8
8
% L
% Met:
8
8
0
0
8
0
0
8
0
29
8
0
0
0
8
% M
% Asn:
0
0
8
72
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
8
0
0
15
36
0
0
% R
% Ser:
0
0
0
8
8
0
0
29
0
8
0
15
0
0
8
% S
% Thr:
65
0
0
8
72
0
0
0
0
0
15
8
0
0
58
% T
% Val:
0
8
8
0
0
22
8
8
0
22
15
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _