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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
23.64
Human Site:
S611
Identified Species:
40
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
S611
L
S
S
A
R
N
F
S
N
M
D
D
E
E
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
S610
L
S
S
A
R
N
F
S
N
M
D
D
E
E
N
Dog
Lupus familis
XP_536569
779
88803
S611
L
S
S
A
R
N
F
S
N
M
D
D
E
E
N
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
A611
L
S
S
A
R
S
F
A
N
M
D
D
E
E
N
Rat
Rattus norvegicus
Q4V8C2
777
87948
A609
L
S
S
A
R
S
F
A
N
M
D
D
E
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
L493
I
R
Q
V
L
H
Q
L
K
R
L
G
M
V
W
Chicken
Gallus gallus
NP_989914
753
85635
S585
L
S
S
A
R
N
F
S
N
M
D
D
E
E
N
Frog
Xenopus laevis
NP_001131044
776
88019
S608
L
S
N
A
R
N
F
S
N
I
E
D
E
D
N
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
S602
L
S
T
A
R
N
F
S
N
L
D
D
E
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
P575
T
H
T
L
G
S
G
P
L
K
L
V
R
Q
C
Honey Bee
Apis mellifera
XP_001121600
710
82808
E564
S
E
L
H
P
N
T
E
R
A
M
R
Q
C
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
A590
D
A
E
N
V
T
S
A
N
R
A
I
K
Q
V
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
Q591
Q
N
T
H
Q
V
Q
Q
F
E
S
A
K
F
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
S595
S
I
D
Q
V
V
F
S
L
K
N
V
H
M
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
0
100
73.3
86.6
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
58
0
0
0
22
0
8
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
50
58
0
8
0
% D
% Glu:
0
8
8
0
0
0
0
8
0
8
8
0
58
50
0
% E
% Phe:
0
0
0
0
0
0
65
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
8
0
15
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
8
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
15
0
0
15
0
0
% K
% Leu:
58
0
8
8
8
0
0
8
15
8
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
43
8
0
8
8
0
% M
% Asn:
0
8
8
8
0
50
0
0
65
0
8
0
0
0
65
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
8
0
15
8
0
0
0
0
8
15
0
% Q
% Arg:
0
8
0
0
58
0
0
0
8
15
0
8
8
0
0
% R
% Ser:
15
58
43
0
0
22
8
50
0
0
8
0
0
0
8
% S
% Thr:
8
0
22
0
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
15
15
0
0
0
0
0
15
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _