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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
12.42
Human Site:
S197
Identified Species:
21.03
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
S197
P
P
S
K
D
T
S
S
L
E
S
Y
L
Q
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
S197
P
P
S
K
D
T
S
S
L
E
S
Y
L
Q
T
Dog
Lupus familis
XP_536569
779
88803
N197
P
P
S
K
D
T
S
N
L
E
S
F
L
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
S197
P
P
A
K
D
T
S
S
L
E
S
C
L
Q
T
Rat
Rattus norvegicus
Q4V8C2
777
87948
S196
F
P
P
S
K
D
T
S
S
L
E
S
C
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
S103
E
L
H
A
K
L
R
S
F
S
Q
L
L
L
N
Chicken
Gallus gallus
NP_989914
753
85635
I194
L
P
S
K
E
E
E
I
A
G
P
P
V
A
S
Frog
Xenopus laevis
NP_001131044
776
88019
S196
L
P
P
S
K
E
N
S
S
M
E
M
I
L
K
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
E195
K
L
P
S
T
K
T
E
L
T
G
A
K
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
V185
E
C
Y
E
T
I
K
V
K
Y
H
V
Q
A
Y
Honey Bee
Apis mellifera
XP_001121600
710
82808
S174
N
L
Y
T
S
F
L
S
D
T
S
L
L
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
G195
K
P
V
E
G
S
K
G
K
A
S
K
S
I
I
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
A195
L
V
K
F
V
E
N
A
V
Q
F
E
P
D
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
N197
V
L
A
K
F
M
E
N
A
V
R
F
E
L
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
13.3
N.A.
13.3
20
13.3
6.6
N.A.
0
20
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
20
N.A.
13.3
40
26.6
13.3
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
0
0
0
8
15
8
0
8
0
15
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
0
% C
% Asp:
0
0
0
0
29
8
0
0
8
0
0
0
0
8
8
% D
% Glu:
15
0
0
15
8
22
15
8
0
29
15
8
8
0
0
% E
% Phe:
8
0
0
8
8
8
0
0
8
0
8
15
0
0
8
% F
% Gly:
0
0
0
0
8
0
0
8
0
8
8
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
8
8
8
% I
% Lys:
15
0
8
43
22
8
15
0
15
0
0
8
8
0
8
% K
% Leu:
22
29
0
0
0
8
8
0
36
8
0
15
43
36
0
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
15
15
0
0
0
0
0
0
8
% N
% Pro:
29
58
22
0
0
0
0
0
0
0
8
8
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
8
29
8
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
29
22
8
8
29
50
15
8
43
8
8
8
15
% S
% Thr:
0
0
0
8
15
29
15
0
0
15
0
0
0
0
29
% T
% Val:
8
8
8
0
8
0
0
8
8
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
0
0
0
8
0
15
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _