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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZW10
All Species:
15.45
Human Site:
S107
Identified Species:
26.15
UniProt:
O43264
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43264
NP_004715.1
779
88829
S107
E
R
D
S
V
V
L
S
L
L
K
Q
L
Q
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085694
778
88561
S107
E
R
D
S
V
V
L
S
L
L
K
Q
L
Q
E
Dog
Lupus familis
XP_536569
779
88803
S107
E
R
D
S
V
V
L
S
L
L
K
Q
L
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
O54692
779
88044
T107
E
R
D
S
V
V
L
T
L
L
K
Q
L
Q
E
Rat
Rattus norvegicus
Q4V8C2
777
87948
N107
E
R
D
S
V
V
L
N
L
L
K
Q
L
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507667
639
71489
P17
G
R
L
A
R
H
L
P
C
P
Q
R
A
Y
G
Chicken
Gallus gallus
NP_989914
753
85635
Y107
T
A
L
L
E
K
R
Y
I
E
A
A
Q
Q
L
Frog
Xenopus laevis
NP_001131044
776
88019
G107
E
K
N
T
L
I
L
G
V
L
K
Q
L
Q
E
Zebra Danio
Brachydanio rerio
NP_956435
771
87302
D107
E
K
N
T
A
V
I
D
L
L
Q
H
L
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4X9
721
82245
K99
A
L
D
E
A
N
V
K
M
A
G
N
G
R
Q
Honey Bee
Apis mellifera
XP_001121600
710
82808
S88
V
K
I
E
L
S
G
S
T
K
E
L
K
T
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789289
745
83639
A107
D
Q
S
N
A
T
I
A
V
L
T
T
L
C
K
Poplar Tree
Populus trichocarpa
XP_002301597
767
86905
K107
I
V
E
E
L
S
G
K
M
K
E
A
R
E
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O48626
742
83915
E109
S
V
V
D
E
I
T
E
K
T
K
E
V
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
91.5
N.A.
86.1
85.3
N.A.
60.7
68.1
70.4
60.2
N.A.
23.3
31.7
N.A.
39.2
Protein Similarity:
100
N.A.
99.3
95.1
N.A.
92.5
92
N.A.
71.2
82.6
84.8
77.6
N.A.
41
52.2
N.A.
59.3
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
13.3
6.6
53.3
46.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
13.3
93.3
80
N.A.
33.3
26.6
N.A.
60
Percent
Protein Identity:
22.2
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
45.1
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
22
0
0
8
0
8
8
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
8
0
43
8
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
50
0
8
22
15
0
0
8
0
8
15
8
0
8
43
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
15
8
0
0
8
0
8
0
8
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
8
0
0
15
15
0
8
0
0
0
0
0
0
% I
% Lys:
0
22
0
0
0
8
0
15
8
15
50
0
8
8
15
% K
% Leu:
0
8
15
8
22
0
50
0
43
58
0
8
58
0
22
% L
% Met:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% M
% Asn:
0
0
15
8
0
8
0
8
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
15
43
8
58
15
% Q
% Arg:
0
43
0
0
8
0
8
0
0
0
0
8
8
8
0
% R
% Ser:
8
0
8
36
0
15
0
29
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
15
0
8
8
8
8
8
8
8
0
8
0
% T
% Val:
8
15
8
0
36
43
8
0
15
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _