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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLK10
All Species:
13.03
Human Site:
S56
Identified Species:
40.95
UniProt:
O43240
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43240
NP_001070968.1
276
30138
S56
G
A
P
C
A
R
G
S
Q
P
W
Q
V
S
L
Chimpanzee
Pan troglodytes
XP_001174071
276
30097
S56
G
A
P
C
A
R
G
S
Q
P
W
Q
V
S
L
Rhesus Macaque
Macaca mulatta
XP_001114486
249
27181
H43
L
F
N
G
L
S
F
H
C
A
G
V
L
V
D
Dog
Lupus familis
XP_541467
603
66108
S118
G
A
P
C
A
R
G
S
Q
P
W
Q
V
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91VE3
249
27239
A42
G
S
H
P
W
Q
V
A
L
L
K
G
N
Q
L
Rat
Rattus norvegicus
O88780
260
28491
S43
G
Q
E
C
K
P
H
S
Q
P
W
Q
T
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90629
248
26604
G46
Y
Q
V
S
L
N
S
G
Y
H
F
C
G
G
S
Frog
Xenopus laevis
P70059
244
26061
S49
G
Y
H
F
C
G
G
S
L
I
N
S
Q
W
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
88.4
39.6
N.A.
38
38.7
N.A.
N.A.
37.3
35.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
89.1
42.7
N.A.
56.1
52.5
N.A.
N.A.
56.8
53.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
13.3
53.3
N.A.
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
33.3
60
N.A.
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
38
0
0
38
0
0
13
0
13
0
0
0
13
0
% A
% Cys:
0
0
0
50
13
0
0
0
13
0
0
13
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% D
% Glu:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
13
0
0
13
0
0
0
13
0
0
0
0
% F
% Gly:
75
0
0
13
0
13
50
13
0
0
13
13
13
13
0
% G
% His:
0
0
25
0
0
0
13
13
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
0
0
0
0
13
0
0
0
0
% K
% Leu:
13
0
0
0
25
0
0
0
25
13
0
0
13
0
63
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
13
0
0
0
0
13
0
13
0
0
% N
% Pro:
0
0
38
13
0
13
0
0
0
50
0
0
0
0
0
% P
% Gln:
0
25
0
0
0
13
0
0
50
0
0
50
13
13
0
% Q
% Arg:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
13
0
13
0
13
13
63
0
0
0
13
0
38
13
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
13
0
0
0
13
0
0
0
0
13
38
13
13
% V
% Trp:
0
0
0
0
13
0
0
0
0
0
50
0
0
13
0
% W
% Tyr:
13
13
0
0
0
0
0
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _