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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC1LI2
All Species:
31.52
Human Site:
S425
Identified Species:
69.33
UniProt:
O43237
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43237
NP_006132.1
492
54099
S425
N
I
K
N
N
A
A
S
E
G
V
L
A
S
F
Chimpanzee
Pan troglodytes
XP_001167584
472
51615
S389
N
M
K
A
G
A
T
S
E
G
V
L
A
N
F
Rhesus Macaque
Macaca mulatta
XP_001085468
497
54504
S430
N
I
K
N
N
A
A
S
E
G
V
L
A
S
F
Dog
Lupus familis
XP_536823
481
53613
S414
N
I
K
N
N
A
A
S
E
G
V
L
A
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDL0
492
54199
S425
N
I
K
N
N
A
A
S
E
G
V
L
A
S
F
Rat
Rattus norvegicus
Q62698
497
54726
S411
N
I
K
N
N
A
A
S
E
G
V
L
A
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508928
471
51509
S400
N
F
F
N
S
L
L
S
K
K
T
G
S
P
G
Chicken
Gallus gallus
Q90828
515
55875
S430
N
M
K
A
G
A
T
S
E
G
V
L
A
N
F
Frog
Xenopus laevis
NP_001090295
487
53506
S418
N
I
K
N
A
A
A
S
E
G
V
L
A
S
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395283
470
52288
K402
I
G
A
S
S
P
N
K
K
L
D
P
K
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795494
483
53698
G416
G
K
P
K
I
D
P
G
K
P
G
S
A
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63
95.5
91.8
N.A.
96.7
93.5
N.A.
62.7
64.8
81.5
N.A.
N.A.
N.A.
47.3
N.A.
51.6
Protein Similarity:
100
74.3
96.7
93.2
N.A.
99.1
95.3
N.A.
75
77
89.4
N.A.
N.A.
N.A.
63.2
N.A.
69.3
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
20
66.6
93.3
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
40
80
93.3
N.A.
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
19
10
73
55
0
0
0
0
0
82
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
10
% E
% Phe:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
73
% F
% Gly:
10
10
0
0
19
0
0
10
0
73
10
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
55
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
73
10
0
0
0
10
28
10
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
10
10
0
0
10
0
73
0
0
0
% L
% Met:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
82
0
0
64
46
0
10
0
0
0
0
0
0
28
0
% N
% Pro:
0
0
10
0
0
10
10
0
0
10
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
19
0
0
82
0
0
0
10
10
55
0
% S
% Thr:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
73
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _