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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT4 All Species: 8.48
Human Site: Y92 Identified Species: 18.67
UniProt: O43236 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43236 NP_004565.1 478 55098 Y92 Q S S D N Q Q Y F C A P A P L
Chimpanzee Pan troglodytes Q5R1W1 434 50272 V95 V Q V E Q S K V L I K E G G V
Rhesus Macaque Macaca mulatta XP_001104631 578 65159 Y192 Q S A D N Q Q Y F C A P A P L
Dog Lupus familis XP_537693 331 38609
Cat Felis silvestris
Mouse Mus musculus P28661 478 54917 Y92 Q P S D S Q Q Y F S A P A P L
Rat Rattus norvegicus Q9JJM9 369 42834 N32 V G F A T L P N Q V H R K S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509185 527 59238 H135 W P P D G H Q H I S A P A P L
Chicken Gallus gallus Q5ZMH1 349 40206 D12 G E K V K F S D S A G Y V G F
Frog Xenopus laevis Q63ZQ1 352 40432 G15 F T N P E T P G Y V G F A N L
Zebra Danio Brachydanio rerio A2BGU8 361 40623 P24 A K P S H V A P P S S A P F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42207 361 41113 Q24 G F A N L P N Q V H R K S V K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.7 80.4 67.3 N.A. 92.6 60 N.A. 69 47.2 47 37.2 N.A. 47.4 N.A. N.A. N.A.
Protein Similarity: 100 59.4 80.8 68.4 N.A. 95.1 68.1 N.A. 76 59.8 59 52.9 N.A. 60.8 N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 0 N.A. 80 0 N.A. 46.6 0 13.3 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 0 N.A. 86.6 6.6 N.A. 53.3 0 33.3 20 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 10 0 0 10 0 0 10 37 10 46 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 % C
% Asp: 0 0 0 37 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 10 10 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 10 10 10 0 0 10 0 0 28 0 0 10 0 10 10 % F
% Gly: 19 10 0 0 10 0 0 10 0 0 19 0 10 19 0 % G
% His: 0 0 0 0 10 10 0 10 0 10 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % I
% Lys: 0 10 10 0 10 0 10 0 0 0 10 10 10 0 10 % K
% Leu: 0 0 0 0 10 10 0 0 10 0 0 0 0 0 46 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 10 19 0 10 10 0 0 0 0 0 10 0 % N
% Pro: 0 19 19 10 0 10 19 10 10 0 0 37 10 37 0 % P
% Gln: 28 10 0 0 10 28 37 10 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % R
% Ser: 0 19 19 10 10 10 10 0 10 28 10 0 10 10 0 % S
% Thr: 0 10 0 0 10 10 0 0 0 0 0 0 0 0 0 % T
% Val: 19 0 10 10 0 10 0 10 10 19 0 0 10 10 28 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 28 10 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _